Evidence map›Paper›PMID 41772356›Full record

ArticleJournal of neurovirology2026

CSF CXCL13 as a longitudinal marker for neurocognition in HIV-1-associated dementia after start of treatment in cART-naïve patients.

Jürgen Panholzer, Anna R Tröscher, Vincent Böhm, Raimund Helbok, Christian Eggers

Abstract read
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Article in Journal of neurovirology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jürgen PanholzerDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, Krankenhausstraße 9, Linz, 4021, Austria.
Anna R TröscherDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, Krankenhausstraße 9, Linz, 4021, Austria.
Vincent BöhmDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, Krankenhausstraße 9, Linz, 4021, Austria.
Raimund HelbokDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, Krankenhausstraße 9, Linz, 4021, Austria.
Christian EggersDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, Krankenhausstraße 9, Linz, 4021, Austria. Christian.Eggers@kepleruniklinikum.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite suppression of viral replication by antiretroviral therapy (cART) HIV-associated neurocognitive disorders (HAND) may persist. This involves chronic inflammation with activation of the monocyte-macrophage-microglia axis. We examined CXCL13, a chemokine released by these cells, as a possible marker for HAND treatment response. We longitudinally analyzed cerebrospinal fluid (CSF) from before and during newly initiated cART of people living with HIV (PLWH) with HIV-associated dementia (HAD). CXCL13

Indexed as

AIDS dementia complexAntiretroviral therapy, highly activeChemokine CXCL13HIVNeurocognitive disorders

Identifiers

PMID41772356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.