ArticleNatural products and bioprospecting2026
Peniexpansones A-F: polyketides from Penicillium expansum DWS880 capable of enhancing the activity of fluconazole against Candida albicans.
Article in Natural products and bioprospecting, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Periconoid A, a Novel Ergosterol Derivative fromMarine drugs · 2026Article
- Design and optimization of mucoadhesive chitosan microspheres for oesophageal delivery of fluconazole.Frontiers in drug delivery · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Six new polyketides, peniexpansones A-F (1-4, 6, 7), along with an additional novel compound, (2E,4E,6E)-8-methyldeca-2,4,6-trienoic acid (5), and a known naphthopyrone, were isolated from the ethyl acetate extract of rice fermented with the soil fungus Penicillium expansum DWS880. Structurally, peniexpansones A-D feature a highly oxygenated tetrahydronaphthalene moiety linked to an acyl chain. The structures of the new compounds were elucidated by extensive spectroscopic analysis (1D/2D NMR and HRESIMS) and further supported by quantum chemical calculations. Peniexpansone C showed weak cytotoxicity against HCT116 cells (IC
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Registered trials
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