Evidence map›Paper›PMID 41772254›Full record

ArticleNPJ digital medicine2026

Construction of virtual whole eye model based on ultra-widefield optical coherence tomography in myopia.

Xiangcheng Tang, Na Luo, Caiyi Chen, Pengsen Wu, Wenjun Guo, Yitong Shen, Juntao Jiang, Mingzhu Fu, Li Huo, Jingfeng Mu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiangcheng TangShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Na LuoShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Caiyi ChenShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Pengsen WuShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Wenjun GuoShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Yitong ShenDepartment of Physiology, School of Medical Sciences, New Zealand Eye Centre, University of Auckland, Auckland, New Zealand.
Juntao JiangCollege of Control Science and Engineering, Zhejiang University, Hangzhou, China.
Mingzhu FuDepartment of electronic engineering, Tsinghua University, Beijing, China.
Li HuoDepartment of electronic engineering, Tsinghua University, Beijing, China.
Jingfeng MuShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Meizhou LiuShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Guiqin LiuShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China.
Shaochong ZhangShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China. shaochongzhang@outlook.com.
Xingzheng PanDepartment of Physiology, School of Medical Sciences, New Zealand Eye Centre, University of Auckland, Auckland, New Zealand. x.pan@auckland.ac.nz.
Wei ChiShenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China. chiwei@mail.sysu.edu.cn.

Funding

Guangdong Basic and Applied Basic Research Foundation Regional Joint Fund Key Program 2023B1515120051the Key Project Fund of National Natural Science Foundation 82230031the Key Special Project of 'Cutting-Edge Biotechnology' in the National Key Research and Development Program of China 2024YFC3406200the Regional Innovation and Development Joint Fund of the National Natural Science Foundation of China U24A200954the Sanming Project of Medicine in Shenzhen No. SZSM202411007
6 · The paper itself

Abstract

Recognizing the inconvenience of magnetic resonance imaging (MRI) in evaluating the ocular morphology, this study developed a three-dimensional virtual whole eye model (CET-1) using ultra-widefield swept-source optical coherence tomography. The CET-1 were validated with MRI models in 80 eyes from 40 individuals with different extent of myopia. The result showed these two models have high consistency across different axial lengths (22.19 to 32.56 mm) -calculated as the mean point-to-surface distance, measuring 0.0183 ± 0.0025 normalized unit (439.57 ± 59.87 μm). Compared to the normal group, both of the posterior segment Gaussian curvature and anterior segment parameters demonstrated a significant change in myopic groups (P < 0.05). The CET-1 model provides a simple and effective tool that enables the establishment of a digital twin ocular model, facilitating the monitoring and quantitative analysis of myopia development and progression. Thus, supports optimized treatment strategies and contributes to the advancement of personalized medicine.

Identifiers

PMID41772254
PMCPMC13066525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.