Evidence map›Paper›PMID 41772236›Full record

Observational studyWorld journal of surgery2026

How Is Colorectal Cancer Care Impacted by Global Crisis in Contrasting Healthcare Systems?-A Descriptive Study From Scotland and Switzerland During the COVID-19 Pandemic.

B Wiesler, M Worni, P Studer, J-M Gass, J Metzger, M Hartel, C Nebiker, R Rosenberg, R Galli, L Eisner and 14 more

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04550156 (Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04550156 nacompletednot on this map

Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections

TypeinterventionalSponsorUniversity Hospital, Basel, SwitzerlandRan2020 to 2022Enrolled1,141ConditionsColorectal Disorders, Surgery--Complications, Colorectal Cancer, Anastomotic LeakArmsColorectal Bundle
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

B WieslerClarunis, Department of Visceral Surgery, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-2994-0237
M WorniClarunis, Department of Visceral Surgery, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.
P StuderStiftung Lindenhof I Campus SLB, Swiss Institute for Translational and Entrepreneurial Medicine, Berne, Switzerland.
J-M GassDepartment of Visceral Surgery, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
J MetzgerDepartment of Visceral Surgery, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
M HartelDepartment of Visceral Surgery, Cantonal Hospital of Aarau, Aarau, Switzerland.
C NebikerDepartment of Visceral Surgery, Cantonal Hospital of Aarau, Aarau, Switzerland.
R RosenbergDepartment of Visceral Surgery, Cantonal Hospital of Basel-Land, Liestal, Switzerland.
R GalliDepartment of Visceral Surgery, Cantonal Hospital of Basel-Land, Liestal, Switzerland.
L EisnerDepartment of Surgery, Cantonal Hospital of Olten, Olten, Switzerland.
C AndreouDepartment of Surgery, Cantonal Hospital of Olten, Olten, Switzerland.
U ZinggDepartment of Visceral Surgery, Spital Limmattal, Schlieren, Switzerland.
D StimpfleDepartment of Visceral Surgery, Spital Limmattal, Schlieren, Switzerland.
C T ViehlDepartment of Surgery, Spitalzentrum Biel, Biel, Switzerland.
A MüllerDepartment of Surgery, Spitalzentrum Biel, Biel, Switzerland.
B MüllerClarunis, Department of Visceral Surgery, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.
K DenhaerynckDepartment of Public Health, University of Basel, Basel, Switzerland.
P HallEdinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Scotland.
C GallagherEdinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Scotland.
P KarunaratneEdinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Scotland.
C LilleyEdinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, Scotland.
M ZuberClarunis, Department of Visceral Surgery, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.
H PatersonDepartment of Colorectal Surgery, Western General Hospital, Edinburgh, Scotland.
M von Strauss Und TorneyClarunis, Department of Visceral Surgery, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0003-1872-2397

Funding

Krebsliga Beider Basel KLbB-5330-03-2021
6 · The paper itself

Abstract

backgroundHealthcare across Europe was affected by COVID-19 pandemic lockdowns. How different national healthcare systems coped with this impact remains unclear. Healthcare in Switzerland differs significantly from that in Scotland, for example, in terms of centralization. The aim of this study was to assess the impact of the COVID-19 pandemic on the diagnosis and surgical treatment of colorectal cancer (CRC) in contrasting healthcare systems. PATIENTS AND

methodsThis retrospective cohort study was conducted in south-east Scotland and in the extended north-west of Switzerland from January 1st, 2019 to February 28th, 2023. All patients diagnosed with CRC were included. The primary outcomes were the time from CRC diagnosis to treatment and the UICC stage at diagnosis, assessed prior to, during, and following the period of lockdown. The lockdown in Scotland lasted from March 2020 to October 2020 and in Switzerland from March 2020 to April 2020.

resultsA total of 6745 patients were included (4127 from Scotland and 2618 from Switzerland). Median time from diagnosis to treatment remained unaltered during the lockdown period in both countries. However, after the lockdown, the median time from diagnosis to treatment increased from 59 to 76 days in Scotland. The median number of patients who were diagnosed per annual quarter declined from 177 (IQR: 171-190) to 152 (IQR: 150-154), and the median number of who received treatment from declined from 256 (IQR: 253-259) to 203 (IQR: 186-218) during lockdown in Scotland. In multivariable logistic regression, the odds of being diagnosed with UICC stage IV increased by 42% for patients diagnosed during lockdown (95%-CI: 12%-81%). In Switzerland, the time from diagnosis to treatment increased slightly after the pandemic. However, the other effects described above were not observed in Switzerland.

conclusionsThis descriptive study demonstrated that the impact of the pandemic on colorectal cancer care was less pronounced in Switzerland, but considerable in Scotland. Because separate subgroup analyses were conducted, direct comparisons cannot be made between Scotland and Switzerland.

trial registrationThis trial is registered on clinicaltrials.gov as part of the EvaCol study (NCT04550156).

Indexed as

Colorectal NeoplasmsCOVID-19Delivery of Health CarePandemicsAgedColorectal Surgical ProceduresFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicRetrospective StudiesSARS-CoV-2ScotlandSwitzerlandTime-to-Treatmentcentralizationcolorectal cancerpandemic

Identifiers

PMID41772236
PMCPMC13070440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.