Evidence map›Paper›PMID 41772174›Full record

ArticleNature biomedical engineering2026

Leveraging tissue-resident memory T cells for non-invasive immune monitoring via microneedle skin patches.

Sasan Jalili, Ryan R Hosn, Wei-Che Ko, Khashayar Afshari, Ashok Kumar Dhinakaran, Namit Chaudhary, Laura Maiorino, Nazgol-Sadat Haddadi, Anusha Nathan, Matthew A Getz and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Sasan JaliliKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. sasan.Jalili@jax.org.ORCID http://orcid.org/0000-0002-5004-893X
Ryan R HosnKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-0818-8031
Wei-Che KoDepartment of Dermatology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Khashayar AfshariDepartment of Dermatology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Ashok Kumar DhinakaranThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.ORCID http://orcid.org/0000-0002-0056-1284
Namit ChaudharyKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Laura MaiorinoKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nazgol-Sadat HaddadiDepartment of Dermatology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Anusha NathanRagon Institute of Mass General Brigham, MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-4418-1005
Matthew A GetzRagon Institute of Mass General Brigham, MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-4172-2187
Gaurav D GaihaDivision of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.
Mehdi RashighiDepartment of Dermatology, University of Massachusetts Chan Medical School, Worcester, MA, USA.ORCID http://orcid.org/0000-0002-9170-5887
John E HarrisDepartment of Dermatology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Paula T HammondKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-9835-192X
Darrell J IrvineKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. djirvine@scripps.edu.ORCID http://orcid.org/0000-0002-8637-1405

Funding

Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Predictive drivers of new onset, relapse, and progression of human autoimmunity in skinU01AI176310 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Manuel Garber, John E Harris · 2023 to 2026
$5.3M
Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) U01AI176310NIGMS NIH HHS T32 GM144273U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) P30-CA1405U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U01AI176310
6 · The paper itself

Abstract

Detecting antigen-specific lymphocytes is crucial for immune monitoring in vaccination, infection, cancer and autoimmunity. However, their low frequency and dispersed distribution make reliable detection challenging. We developed a strategy exploiting the functions of tissue-resident memory T cells (T

Identifiers

PMID41772174

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.