Evidence map›Paper›PMID 41772148›Full record

Observational studyArchives of gynecology and obstetrics2026

Maternal-fetal attachment trajectories in IVF mothers during the first trimester: a prospective observational study.

Xuzhen Cheng, Fangfang Chen, Huiling Huang, Fang Zhang, Xinfen Xu

Abstract readObservational Study
In one paragraph

Observational study in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xuzhen ChengWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Fangfang ChenWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Huiling HuangWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Fang ZhangWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xinfen XuWomen's Hospital, School of Medicine, Zhejiang University, Hangzhou, China. xuxinf@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify trajectories of maternal-fetal attachment (MFA) in IVF mothers during the first trimester of pregnancy, and to explore categorical predictors of subgroups demonstrating MFA trajectories.

methodsA prospective observational study was conducted on 495 IVF mothers. Self-report questionnaires assessing MFA, anxiety, depression, social support, and marital satisfaction were completed at three time points: 3-4 weeks (T1), 7-8 weeks (T2), and 12-14 weeks (T3) of gestation. Repeated measurement data were analyzed and growth trajectories identified.

resultsThree MFA trajectories were delineated in IVF mothers during the first trimester: low-attachment/slow-elevation group (30.9%), moderate-attachment/steady-elevation group (56.2%), and high-attachment/rapid-elevation group (12.9%). Secondary infertility (OR = 0.575, 95% CI: 0.368-0.901, p = 0.013) and higher marital satisfaction (OR = 0.941, 95% CI: 0.915-0.968, p < 0.001) were predictors for not being in the low-attachment/slow-elevation group.

conclusionAmong IVF mothers with ongoing pregnancies, a subset exhibited suboptimal development of MFA during the first trimester. Marital satisfaction and infertility type may help identify those at potential risk.

Indexed as

Fertilization in VitroMaternal-Fetal RelationsMothersObject AttachmentPregnancy Trimester, FirstAdultAnxietyDepressionFemaleHumansPersonal SatisfactionPregnancyProspective StudiesSocial SupportInfertilityMaternal–fetal relationsMental healthPregnancyPrenatal attachment

Identifiers

PMID41772148
PMCPMC12953469

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.