Evidence map›Paper›PMID 41772101›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Congenital heart disease and congenital diaphragmatic hernia: the role of intracardiac shunts.

Jenna A Katz, Philip T Levy, Isabella Zaniletti, Molly K Ball, Ruth Seabrook, Shazia Bhombal, Karna Murthy, Michael A Padula, Sharada H Gowda, Theresa R Grover and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jenna A KatzDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA. jenna.katz@childrens.harvard.edu.ORCID http://orcid.org/0000-0002-4852-6752
Philip T LevyDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5103-5834
Isabella ZanilettiChildren's Hospitals Neonatal Consortium, Dover, DE, USA.ORCID http://orcid.org/0000-0003-1234-3468
Molly K BallDivision of Neonatology, Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID http://orcid.org/0000-0001-7036-0974
Ruth SeabrookDivision of Neonatology, Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-0352-2651
Shazia BhombalChildren's Healthcare of Atlanta, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-4581-246X
Karna MurthyDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Michael A PadulaChildren's Hospitals Neonatal Consortium, Dover, DE, USA.
Sharada H GowdaDivision of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0001-7009-4821
Theresa R GroverSection of Neonatology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.
Sarah D KeeneChildren's Healthcare of Atlanta, Atlanta, GA, USA.
Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the impact of cardiac lesions on outcomes to discharge in infants with congenital diaphragmatic hernia (CDH). STUDY

designRetrospective analysis of infants with CDH identified in the Children's Hospitals Neonatal Database (CHND) from 2010 to 22. Patients were stratified into groups based on associated congenital heart disease (CHD): (1) noCHD (2) CDH + atrial, ventricular septal defects (avCHD); (3) CDH + severe CHD (sevCHD).

resultsAmong 2940 neonates with CDH, 570 (19%) had CHD (453 avCDH, 117 sevCHD). CHD of any severity was associated with small for gestational age at birth, a 5 minute Apgar <5, and additional anomalies or syndromes (p < 0.05 for all). Mechanical ventilation days, use of extra-corporeal membrane oxygenation, length of stay, and mortality increased with CHD severity (p < 0.005). Home medical needs were more frequent in infants with associated CHD (p < 0.001).

conclusionsComorbid CHD of any severity adds complexity and risk to patients with CDH.

Indexed as

Heart Defects, CongenitalHernia, DiaphragmaticHernias, Diaphragmatic, CongenitalAbnormalities, MultipleExtracorporeal Membrane OxygenationFemaleHeart Septal Defects, VentricularHumansInfant, NewbornLength of StayMaleRespiration, ArtificialRetrospective StudiesSeverity of Illness Index

Identifiers

PMID41772101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.