Evidence map›Paper›PMID 41772057›Full record

ReviewNature human behaviour2026

The conceptual landscape of self-regulation in neurodevelopmental conditions: an overview of reviews.

Iciar Iturmendi-Sabater, Sejal Jain, Sofia Turcany-Diaz, Reena Besa, Evdokia Anagnostou, Marc A Fournier, Hsiang-Yuan Lin, Meng-Chuan Lai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature human behaviour, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iciar Iturmendi-SabaterCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Sejal JainCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Sofia Turcany-DiazSussex Neuroscience Centre of Excellence, University of Sussex, Brighton, UK.
Reena BesaDepartment of Education, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-1455-5483
Evdokia AnagnostouInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Marc A FournierDepartment of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada.
Hsiang-Yuan LinCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-9519-209X
Meng-Chuan LaiCampbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. mengchuan.lai@utoronto.ca.ORCID http://orcid.org/0000-0002-9593-5508

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) GSB 171373"la Caixa" Foundation (Caixa Foundation) LCF/BQ/EU21/11890074
6 · The paper itself

Abstract

Self-regulation is critical yet inconsistently defined across neurodevelopmental conditions (NDCs). This preregistered (CRD42023350582), PRISMA-aligned overview of reviews aimed to (1) review and summarize definitions and models of self-regulation, (2) synthesize key self-regulation-related constructs and (3) identify common self-regulation measures in NDC populations. We searched Ovid Medline/PsycINFO/Embase, Web of Science-Core Collection and Cochrane Databases (inception to September 2024). We included 35 narrative, 2 scoping, 7 systematic and 3 meta-analytic peer-reviewed reviews of human studies on autism, attention-deficit/hyperactivity disorder and intellectual disability that addressed self-regulation across emotional, cognitive and behavioural domains. We found that, despite varied terminology, elevated dysregulation was consistently reported across the included reviews. Inductive content analysis of the included reviews identified core psychological constructs related to self-regulation and their developmental and environmental-contextual interplays; the findings converged into a domain-general, transdiagnostic self-regulation framework emphasizing interdependent integration of emotional, cognitive and behavioural processes across contexts. Finally, a meta-summary from 332 primary empirical studies from the included scoping, systematic and meta-analytic reviews (69 autism, 130 intellectual disability and 133 attention-deficit/hyperactivity disorder) revealed measurement gaps with 521 identified measurements relying heavily on parent-report questionnaires. Risk of bias assessed through the Joanna Briggs Institute checklist revealed methodological heterogeneity. This overview of reviews offers guidance for aligning research, assessments and interventions with a domain-general, developmental understanding of self-regulation across NDCs.

Indexed as

Neurodevelopmental DisordersSelf-ControlAttention Deficit Disorder with HyperactivityHumans

Identifiers

PMID41772057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.