Evidence map›Paper›PMID 41771956›Full record

Trial reportScientific reports2026

"Short-term effects of a single kangaroo mother care session on urinary allantoin and maternal-infant bonding in preterm neonates: a quasi-randomized controlled trial".

Samreen Manzoor, Samina Kausar, Ayesha Hanif, Faheem Shahzad, Samina Farooqi, Rafia Khalid

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samreen ManzoorMS Nursing Scholar, University of Health Sciences, Lahore, Pakistan. samreenmanzoor4@gmail.com.ORCID https://orcid.org/0000-0003-2618-4592
Samina KausarProfessor & Head of Nursing Department, University of Health Sciences, Lahore, Pakistan.ORCID https://orcid.org/0009-0006-1088-0445
Ayesha HanifConsultant Paediatrician, Services Hospital, Lahore, Pakistan.
Faheem ShahzadAssistant Professor, Institute of Allied Health Sciences, University of Health Sciences, Lahore, Pakistan.
Samina FarooqiAssistant Professor / Visiting Faculty, Institute of Nursing, University of Health Sciences, Lahore, Pakistan.
Rafia KhalidMPhil Immunology Scholar, University of Health Sciences, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm birth is a leading contributor to neonatal morbidity and mortality, often necessitating neonatal intensive care unit (NICU) admission. The resulting separation of mother-infant dyads may escalate physiological stress and impair early bonding. While Kangaroo Mother Care (KMC) is a well-established intervention, evidence regarding the immediate physiological and affective impact of an isolated, short-duration session remains sparse. Thus, this study aimed to evaluate the short-term effects of a single one-hour KMC session on oxidative stress and maternal-infant bonding in preterm neonates. This quasi-randomized controlled trial was conducted at a tertiary care facility in Lahore, Pakistan (February-July 2024). Forty preterm neonate-mother dyads were allocated based on medical record numbers to receive either a single 60 minute KMC session (n = 20) or standard incubator care (n = 20). Primary and secondary outcomes included urinary allantoin (measured via ELISA) and Mother-Infant Bonding Scale (MIBS) scores, respectively, assessed at baseline and one hour after the intervention. Data were analysed using paired t-tests and analysis of covariance (ANCOVA). Baseline groups were comparable (p>0.05). Post-intervention, KMC significantly reduced allantoin levels compared to controls (Adjusted Mean Difference [AMD]: -26.18 µmol/mmol; 95% CI: -36.88 to -15.48; p<0.001; partial η

Indexed as

AllantoinInfant, PrematureKangaroo-Mother Care MethodMother-Child RelationsObject AttachmentAdultFemaleHumansInfant, NewbornMaleOxidative StressAllantoinKangaroo mother careMaternal–infant bondingOxidative stressPreterm neonatesUrinary allantoin

Identifiers

PMID41771956
PMCPMC12979759

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.