Evidence map›Paper›PMID 41771947›Full record

ArticleScientific reports2026

Regional-specific GABAergic imbalance in cisplatin-induced neuropathy and antiallodynic effects of intraplantar baclofen in rats.

Yingshi Quan, Enji Zhang, Yongshan Nan, Hai Lin

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingshi Quan *Department of Anesthesiology, Yanbian University Hospital, Juzijie, Yanji, 1327, 133000, Jilin Province, PR China.
Enji Zhang *Department of Anesthesiology, Yanbian University Hospital, Juzijie, Yanji, 1327, 133000, Jilin Province, PR China.
Yongshan NanDepartment of Anesthesiology, Yanbian University Hospital, Juzijie, Yanji, 1327, 133000, Jilin Province, PR China.
Hai LinDepartment of Anesthesiology, Yanbian University Hospital, Juzijie, Yanji, 1327, 133000, Jilin Province, PR China. linhai406@gmail.com.

Funding

Natural Science Foundation of Jilin Province YDZJ200401105ZXTS
6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating complication of cisplatin chemotherapy, often manifesting as mechanical allodynia, which frequently resists conventional treatments. This study explored the behavioral and molecular alterations induced by cisplatin, with a focus on regional dysfunction of the gamma-aminobutyric acid (GABA) system, and evaluated the therapeutic potential of intraplantar baclofen (a GABA

Indexed as

BaclofenCisplatinGABA-B Receptor Agonistsgamma-Aminobutyric AcidHyperalgesiaPeripheral Nervous System DiseasesAnimalsAntineoplastic AgentsGanglia, SpinalGlutamate DecarboxylaseMaleRatsRats, Sprague-DawleyReceptors, GABA-BAntineoplastic AgentsBaclofenCisplatinGABA-B Receptor Agonistsgamma-Aminobutyric AcidGlutamate DecarboxylaseReceptors, GABA-BBaclofenChemotherapy-induced peripheral neuropathyCisplatinGABAGABAB receptorMechanical allodynia

Identifiers

PMID41771947
PMCPMC12988107

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.