ArticleScientific reports2026
Nonalcoholic fatty liver disease assessed by multiple tools are correlated to periodontal conditions.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Mechanisms underlying the role of the oral-gut-liver axis in the promotion of liver fibrosis by periodontal disease: an interacting network of inflammation, microbiota, and barrier function.Frontiers in cellular and infection microbiology · 2026Review
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Authors and funding
12 authors.
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Abstract
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis was evaluated using the Community Periodontal Index (CPI), and NAFLD was evaluated using multiple tools such as Fibrosis-4 (FIB4), NAFLD fibrosis score (NFS), and Fatty Liver Index (FLI). The relationship between periodontitis and the cutoff values of three NAFLD assessment tools by logistic regression analyses indicated that PPD ≥ 6 mm was significantly associated with NFS > 0.675 (OR = 4.11, 95%CI:1.06–15.99) and with FLI ≥ 60 (OR = 1.76, 95%CI:1.12–2.76). The participants with BOP positive indicated a significant association between PPD ≥ 6 mm and FLI ≥ 60 (OR = 1.68, 95%CI:1.05–2.70). However, no association was found in participants without BOP. These results suggest that periodontal inflammation is associated with NAFLD, as assessed using the FLI.
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