Evidence map›Paper›PMID 41771801›Full record

ArticleChemistry & biodiversity2026

Comparative Study of Sulfated Polysaccharides From Ulva Lactuca Grown in Tunisia and Morocco: in Vitro Antioxidant Activity and in Vivo Anti-Inflammatory and Anti-Ulcer Effects.

Nourhene Kharrat, Yasmine Touhamia, Rihab Ben Abdallah Kolsi, Khaled Hamden, Rafik Ben Said, Touria Ould Bel Lahcen, Hichem Ben Salah, Noureddine Allouche

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nourhene KharratFaculty of Sciences of Sfax, Laboratory of Organic Chemistry LR17-ES08 (Natural Substances Team), University of Sfax, Tunisia.
Yasmine TouhamiaDepartment of Biology, Faculty of Sciences- Ain Chock, Health and Environment Laboratory, University Hassan II, Casablanca, Morocco.
Rihab Ben Abdallah KolsiFaculty of Sciences of Sfax, Laboratory of Plant Biotechnology, Tunisia.
Khaled HamdenLaboratory of Bioresources: Integrative Biology and Exploiting, Higher Institute of Biotechnology of Monastir, University of Monastir, Tunisia.
Rafik Ben SaidLaboratory of Blue Biotechnology and Aquatic Bioproducts-B3Aqua, National Institute of Marine Sciences and Technologies (INSTM), Salammbô, Tunis, Tunisia.
Touria Ould Bel LahcenDepartment of Biology, Faculty of Sciences- Ain Chock, Health and Environment Laboratory, University Hassan II, Casablanca, Morocco.
Hichem Ben SalahFaculty of Sciences of Sfax, Laboratory of Organic Chemistry LR17-ES08 (Natural Substances Team), University of Sfax, Tunisia.
Noureddine AlloucheFaculty of Sciences of Sfax, Laboratory of Organic Chemistry LR17-ES08 (Natural Substances Team), University of Sfax, Tunisia.ORCID https://orcid.org/0000-0003-0362-492X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a comparative analysis of sulfated polysaccharides extracted from Ulva lactuca collected in Tunisia (PSUT) and Morocco (PSUM). FTIR confirmed the presence of sulfate groups, while GC-MS identified diverse sugar components. Both polysaccharides showed strong antioxidant activity, with DPPH and ABTS radical scavenging rates exceeding 50% at the highest concentrations. In a rat model of gastric ulceration, PSUT and PSUM significantly reduced inflammation and lymphocytic infiltration and lowered the activities of 5-lipoxygenase and myeloperoxidase. Treatment also produced clear antioxidant effects, decreasing hydrogen peroxide by 48% and 61% and reducing TBARS by 65% and 71%, respectively. In addition, both polysaccharides inhibited gastric H

Indexed as

Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAnti-Ulcer AgentsPolysaccharidesStomach UlcerSulfatesUlvaAnimalsBenzothiazolesBiphenyl CompoundsEdible SeaweedsMaleMoroccoPicratesRatsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAnti-Ulcer AgentsBenzothiazolesBiphenyl CompoundsPicratesPolysaccharidesSulfatesSulfonic AcidsAnti‐inflammatory activityAntioxidant activityGastric ulcersSulfated polysaccharidesUlva lactuca

Identifiers

PMID41771801
PMCPMC12953200

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.