Evidence map›Paper›PMID 41771795›Full record

ArticleChemistry & biodiversity2026

Extract of Sapindus saponaria L., a Native Amazonian Plant, Impacts Germ Cell Development and Modulates Longevity.

Ana Carolina Anchieta Adriano, Péterson Alves Santos, Átila Bezerra de Mira, Juliana Souza Terada Nascimento, Patrícia Pereira, Sandro de Vargas Schons

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Carolina Anchieta AdrianoAnimal Diagnostic Center, Federal University Foundation of Rondônia, Rolim de Moura, Brazil.
Péterson Alves SantosLaboratory of Neuropharmacology and Preclinical Toxicology, Institute of Basic Health Sciences, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.
Átila Bezerra de MiraAnimal Diagnostic Center, Federal University Foundation of Rondônia, Rolim de Moura, Brazil.
Juliana Souza Terada NascimentoAnimal Diagnostic Center, Federal University Foundation of Rondônia, Rolim de Moura, Brazil.
Patrícia PereiraLaboratory of Neuropharmacology and Preclinical Toxicology, Institute of Basic Health Sciences, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.
Sandro de Vargas SchonsAnimal Diagnostic Center, Federal University Foundation of Rondônia, Rolim de Moura, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.506777/2020-00
6 · The paper itself

Abstract

Sapindus saponaria L. (S. saponaria), popularly known as "saboeiro" or "monkey soap," is traditionally used in South America for inflammatory, infectious, and dermatological conditions. Despite its wide use, toxicological data remain limited, and the presence of triterpenoid saponins raises safety concerns. This study evaluated the toxicological and antioxidant effects of methanolic extracts from S. saponaria leaves (ESL) and fruit pericarp (ESF) using Caenorhabditis elegans as an in vivo model. ESL and ESF were chemically profiled by ESI-MS/MS, and worms were exposed to 1, 5, and 10 mg/mL of each extract. Endpoints included lethality (LC

Indexed as

AntioxidantsCaenorhabditis elegansLongevityPlant ExtractsSapindusAnimalsDose-Response Relationship, DrugFruitOxidative StressPlant LeavesAntioxidantsPlant ExtractsAmazonian plantsCaenorhabditis eleganslifespanSapindus saponaria L

Identifiers

PMID41771795
PMCPMC12953201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.