Evidence map›Paper›PMID 41771736›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

Expectation Modulates Hedonic Experiences and Midbrain Responses to Sweet Flavor.

Elena Mainetto, Margaret L Westwater, Hisham Ziauddeen, Kelly M J Diederen, Paul C Fletcher

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elena MainettoDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom.
Margaret L WestwaterDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom margaret.westwater@psych.ox.ac.uk pcf22@medschl.cam.ac.uk.ORCID 0000-0002-2918-0979
Hisham ZiauddeenDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom.
Kelly M J DiederenDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, United Kingdom.
Paul C FletcherDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, United Kingdom margaret.westwater@psych.ox.ac.uk pcf22@medschl.cam.ac.uk.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Non-nutritive sweeteners are sugar substitutes that may promote weight management by reducing an individual's calorie intake. It is, however, unclear whether (1) sugar and non-nutritive sweetener elicit distinct orosensory responses in the human brain and (2) whether the neural responses to these flavors are modulated by expectancy. Addressing these questions has direct relevance to our understanding of food choice behavior and how it may be modified in dietary interventions. We screened

Indexed as

Anticipation, PsychologicalDietary SugarsMesencephalonNon-Nutritive SweetenersTaste PerceptionAdultArtificially Sweetened BeveragesFemaleFlavoring AgentsFood PreferencesHealthy VolunteersHumansMagnetic Resonance ImagingMaleYoung AdultDietary SugarsFlavoring AgentsNon-Nutritive Sweetenersdopamingergicexpectanciesfunctional MRIgustatory rewardsugar

Identifiers

PMID41771736
PMCPMC13022526

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.