ArticleMolecular plant pathology2026
Jujube Witches' Broom Phytoplasma Effectors SJP1/2 Manipulate the ZjTCP2-ZjTCP1 Cascade to Repress Leaf Cell Proliferation in Jujube.
Article in Molecular plant pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Leaf development into the final size is spatiotemporally regulated by cell proliferation and expansion. The jujube witches' broom (JWB) phytoplasma effectors SJP1/2 induce small leaves with decreased cell numbers in jujube plants by promoting the accumulation of the CIN-TCP transcription factor ZjTCP2. However, the molecular mechanism underlying SJP1/2-mediated inhibition of leaf cell proliferation remains largely unknown. Here, we report that SJP1/2 repressed cell proliferation by manipulating ZjTCP2 to control the CYC/TB1-TCP transcription factor ZjTCP1-mediated pathway. Compared with the mature leaves of the control lines, overexpression of ZjTCP1 in Arabidopsis resulted in large leaves with increased cell numbers, which was in contrast to the findings in ZjTCP2-overexpressing transgenic jujube plants. Yeast one-hybrid, luciferase and reverse transcription-quantitative PCR assays revealed that ZjTCP2 directly targeted the ZjTCP1 promoter and downregulated its expression. Furthermore, SJP1 induced the degradation of ZjTCP1 protein. ZjTCP1 was highly expressed during early leaf growth and was positively correlated with cell proliferation-related genes, including ANGUSTIFOLIA3 (ZjAN3), AINTEGUMENTA (ZjANT) and B-type CYCLINS1;1 (ZjCYCB1;1). Further investigations confirmed that ZjTCP1 directly bound to and upregulated the expression of ZjAN3, ZjANT and ZjCYCB1;1, whereas these genes were significantly downregulated in both SJP1/2 and ZjTCP2 transgenic jujube plants and JWB phytoplasma-infected jujube trees compared with those in the controls. These results provide a new insight into the molecular mechanism of SJP1/2-induced small-leaf formation through the manipulation of the ZjTCP2-ZjTCP1 cascade in woody plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.