Evidence map›Paper›PMID 41771211›Full record

ArticleJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Dual X-Ray absorptiometry leg length in youth.

Jack S Dooley, Lance C Liu, Bonny Donzella, Donald R Dengel, Megan R Gunnar, Brie M Reid

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Article in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jack S DooleyLaboratory of Integrative Human Physiology, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: doole079@umn.edu.
Lance C LiuLaboratory of Integrative Human Physiology, University of Minnesota, Minneapolis, MN 55455, USA.
Bonny DonzellaInstitute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA.
Donald R DengelLaboratory of Integrative Human Physiology, University of Minnesota, Minneapolis, MN 55455, USA.
Megan R GunnarInstitute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA.
Brie M ReidDepartment of Psychology; Department of Health Sciences; Center for Cognitive and Brain Health, Northeastern University, Boston, MA 02115, USA.

Funding

Early life stress and cardiometabolic health in adolescenceR01HL149709 · NHLBI · UNIVERSITY OF MINNESOTA · PI GUNNAR, MEGAN R · 2020 to 2023
$3.0M
NHLBI NIH HHS R01 HL149709
6 · The paper itself

Abstract

introductionLeg length has been found to be a predictor of the risk cardiovascular disease, metabolic disease and type 2 diabetes. Traditional measures of leg-length are conducted by subtracting seated leg length from standing height. We examined whether dual X-ray absorptiometry (DXA) may provide another accurate method to determine leg length. The data were obtained from a study of adolescents. The aims were to examine the relationship between DXA-derived leg length (DXA-LL) and traditionally derived leg length (T-LL) and determine whether the two types of measures yielded similar associations with measures of cardiometabolic health and bone density.

methods140 adolescents either conceived and reared in their birth families in the United States (BR birth reared, n = 74, 39 female) or internationally adopted prior to age 5 from orphanage-like institutions (PI previously institutionalized, n = 66, 44 female) had their leg length measured using traditional methods and then using whole body DXA scan. DXA-LL was determined using custom regions of interest.

resultsDXA-LL and T-LL measures were nearly perfectly correlated (r (138) =0.96, p < 0.001). However, DXA-LL estimates were less than T-LL estimates (77.75±6.04 vs 78.96±6.00 cm, p < 0.001). The BR group had longer DXA-LL than the PI group (80.67 cm, 74.84 cm) after controlling for age and sex. Controlling for age and sex, longer leg length using DXA-LL was associated with lower glucose, cholesterol, triglycerides, and HDL, and denser bone density. Similar results were obtained with T-LL.

conclusionDXA-LL is an accurate and reliable leg length measurement tool.

Indexed as

Absorptiometry, PhotonLegLeg Length InequalityAdolescentBone DensityChildFemaleHumansMaleAdolescentsBone mineral densityChildrenDual X-ray absorptiometryHeart rate variabilityLeg length

Identifiers

PMID41771211
PMCPMC12973448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.