Trial reportPloS one2026
Visual perturbation training to reduce visual dependency in Parkinson's disease: A randomized controlled trial.
Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05690308 (A Novel Training Method to Reduce Fall Risk in People with Parkinson's Disease), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Novel Training Method to Reduce Fall Risk in People with Parkinson's Disease: the Role of the Balance Organ
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDecreased gait automaticity and increased visual dependency are important contributors to falls in people with Parkinson's disease. The aim of this study was to assess if visual perturbation training during treadmill walking decreases visual dependency in people with Parkinson's disease. MATERIALS AND
methodsFor this randomized controlled trial 25 early-to-mid-stage people with Parkinson's disease (age 50-67y) without regular freezing of gait were randomly assigned to a visual perturbation group or treadmill training-only control group. Both groups trained 2 times per week for 6 weeks. Visual perturbation training consisted of self-paced treadmill walking with perturbations applied as rotations around the sagittal axis and medio-lateral translations of the virtual reality environment. The primary outcome was visual dependency. Secondary outcomes included steady-state spatiotemporal gait parameters (gait speed, step time/length/width/frequency, and cadence), as well as self-reported (near) falls.
resultsGroup x time interaction effects revealed that visual perturbation training significantly decreased visual dependency (p < 0.001) and improved temporal gait characteristics such as step time (p = 0.012), stride time (p = 0.021) and cadence (p = 0.018) compared to treadmill-only controls. However, no significant effects were found for step width, step length, gait speed, and (near) falls. Improvements in visual dependency were negatively correlated to disease progression (p = 0.004). Discussion: Visual perturbation training decreases visual dependency and improves temporal gait parameters in people with Parkinson's disease. Participants in earlier disease stages appear to benefit most from visual perturbation training but additional research is needed. CLINICAL
trial registrationThis study was pre-registered at ClinicalTrials.gov (NCT05690308) on 09/01/2023.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.