Evidence map›Paper›PMID 41770762›Full record

ArticlePLOS global public health2026

Principles and priorities for integrated tuberculosis screening and care: A modified Delphi consensus exercise.

Claire Jacqueline Calderwood, Tenzin Kunor, Mikaela Coleman, Edson Marambire, Uzma Khan, Rosa Herrera, Jeffry Acaba, Zafar Hussain, Diptendu Bhattacharya, Leyla Larsson and 13 more

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Claire Jacqueline CalderwoodClinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-1926-7464
Tenzin KunorWe Are TB, Georgia, United States of America, Atlanta.
Mikaela ColemanInstitute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Edson MarambireThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Uzma KhanDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.
Rosa HerreraAutonomous University of Durango, Mexicali Campus, Mexicali, Mexico.ORCID https://orcid.org/0009-0000-0113-0702
Jeffry AcabaAPCASO, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-4807-9040
Zafar HussainClinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Diptendu BhattacharyaSurvivors Against TB, Delhi, India.
Leyla LarssonInstitute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.
Jose Luis ParedesDepartment of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States of America.
Laura ParamoInstitute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.ORCID https://orcid.org/0000-0003-4992-5330
Márcia ChiluvaneInstituto Nacional de Saúde (INS), Maputo, Mozambique.
Thu-Anh NguyenSydney School of Public Health, University of Sydney, Sydney, Australia.
Hanh Nguyen HongOxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Vietnam.
Marc d'ElbéeUniversity of Bordeaux, National Institute for Health and Medical Research, Research Institute for Sustainable Development, Bordeaux, France.ORCID https://orcid.org/0000-0002-8827-019X
Eneyi KpokiriClinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Luan Nguyen Quang VoFriends for International TB Relief, Ha Noi, Viet Nam.
Tom WingfieldDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8433-6887
Ben MaraisSydney Infectious Diseases Institute, University of Sydney, Sydney, Australia.
Madhavi BhargavaDepartment of Community Medicine, Yenepoya Medical College, Mangalore, India.ORCID https://orcid.org/0000-0001-7480-566X
Sarah BernaysSydney Infectious Diseases Institute, University of Sydney, Sydney, Australia.
Katharina KranzerClinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis predominates in communities with multiple health and socioeconomic vulnerabilities. Tuberculosis diagnosis presents an opportunity for expanded health services to tuberculosis-affected households. We conducted a modified Delphi process to ascertain if and how expanded services should be offered to people with tuberculosis and their households. Purposively invited panellists were identified through professional networks and included researchers, service providers, policymakers and members of tuberculosis-affected communities. Panellists completed two online survey rounds. Round one sought to establish consensus on the perceived value of integration and capture diverse views on service integration priorities through free-text responses. Round two explored broad consensus statements (consensus defined as ≥75% agreement) developed from round one responses using Likert scales and country-specific priorities. Free-text responses were analysed using inductive thematic analysis. The percentage of panellists agreeing with each statement was calculated as a proportion of all responses, overall and by pre-specified subgroups of professional categories and WHO region. In round one, 223 panellists from 44 countries indicated strong support for expanded and better integrated services for people with tuberculosis (98% agreement), and their household contacts (84%). In round two, 324 people from 68 countries reached consensus on key motivations for service integration. These included improved tuberculosis treatment and other health outcomes among people with tuberculosis, and increased tuberculosis screening and preventive treatment uptake among contacts. Almost all (>99%) panellists agreed that people with tuberculosis should be routinely screened for relevant non-tuberculosis conditions, but only 69% thought this was appropriate among household contacts. There was consensus (93%) that population-wide tuberculosis screening should be integrated with other disease screening. Multiple, often context-specific, considerations for implementation were highlighted. Integrated tuberculosis screening and care is highly valued by global tuberculosis experts. This international consensus provides a strong mandate for research evaluating the feasibility and effectiveness of integrated tuberculosis service delivery and further policy and guideline development.

Identifiers

PMID41770762
PMCPMC12952631

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.