Evidence map›Paper›PMID 41770512›Full record

ArticleJournal of cancer survivorship : research and practice2026

Social information processing in survivors of pediatric brain tumors.

Hailey M Zwicker, Courtney Tromburg, Heide Adham, Mehak Stokoe, Caitlin Forbes, Oluwaseyi A Lawal, Simone Garneau, Araby Roberts, Taryn Fay-McClymont, Gregory M T Guilcher and 6 more

Abstract read
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In one paragraph

Article in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hailey M ZwickerHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada.
Courtney TromburgHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada.
Heide AdhamHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada.
Mehak StokoeWerklund School of Education, University of Calgary, Calgary, AB, Canada.
Caitlin ForbesDepartment of Oncology, Arthur J.E. Child Comprehensive Cancer Centre, University of Calgary, 3395 Hospital Drive N.W, Calgary, AB, T2N5G2, Canada.
Oluwaseyi A LawalDepartment of Oncology, Arthur J.E. Child Comprehensive Cancer Centre, University of Calgary, 3395 Hospital Drive N.W, Calgary, AB, T2N5G2, Canada.
Simone GarneauDepartment of Psychology, University of Calgary, Calgary, AB, Canada.
Araby RobertsDepartment of Oncology, Arthur J.E. Child Comprehensive Cancer Centre, University of Calgary, 3395 Hospital Drive N.W, Calgary, AB, T2N5G2, Canada.
Taryn Fay-McClymontDepartment of Pediatrics, University of Calgary, Calgary, AB, Canada.
Gregory M T GuilcherHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada.
Lucie Lafay-CousinHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada.
Derek S TsangRadiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Natalie LogieDepartment of Oncology, Arthur J.E. Child Comprehensive Cancer Centre, University of Calgary, 3395 Hospital Drive N.W, Calgary, AB, T2N5G2, Canada.
Keith O YeatesDepartment of Psychology, University of Calgary, Calgary, AB, Canada.
Kevin R KrullDepartment of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
Fiona S M SchulteHematology, Oncology, Transplant Program, Alberta Children's Hospital, Calgary, AB, Canada. fiona.schulte@ucalgary.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurvivors of pediatric brain tumors (BT) experience significant, long-term adverse treatment-related effects, such as social deficits-which can impact academic achievement, quality of life, and daily adaptive functioning. Affective processing remains underexplored. This study investigated social affective processing in survivors compared to healthy children (HC), identified clinical and sociodemographic factors that may be related to affective processing, and explored whether cognitive-executive function mediates these relationships.

methodsSurvivors (N = 33, 54.5% female, mean [SD] age = 13.94 [3.28] years) and HC (N = 35, 48.6% female, age = 11.61 [2.96] years) completed behavioral assessments and questionnaires examining affective processing (emotion perception, emotion recognition, and theory of mind), cognitive-executive processes (executive function and inattention), and sociodemographic information (sex, income, parent education, and parent age). Mann-Whitney U compared social affective processing between survivors and HC. Correlations and linear regression examined relationships between predictors of interest and affective processing.

resultsSurvivors performed worse than HC on emotion perception (Z = -2.13, p = .033), but not other social affective tasks. Regression analysis revealed that receiving radiation was associated with poorer emotion perception (t = -3.45, p = .002) and higher inattention scores (t = 2.48, p = .020) while greater time since diagnosis was not. DISCUSSION: Emotion perception is a key component of social information processing and appears compromised in BT survivors, especially those who received radiation therapy, compared to HC. IMPLICATIONS FOR CANCER SURVIVORS: These novel findings highlight potential affective mechanisms underlying social deficits in BT survivors and underscore the need for early screening and targeted interventions to enhance their social well-being.

Indexed as

Affective processingBrain tumorEmotion recognitionOncologyPediatricPsychosocialTheory of mind

Identifiers

PMID41770512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.