Evidence map›Paper›PMID 41770375›Full record

ArticleMikrochimica acta2026

Highly sensitive enantiomeric detection of tryptophan using microchannel-based chiral sensors.

Yueyue Feng, Shiwei Xu, Guofeng Wang, Liying Huang, Zhongyu Yang, Jiacheng Dong, Yu Zhang, Nannan Liu, Chao Deng, Yajun Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yueyue FengKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Shiwei XuKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Guofeng WangKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Liying HuangKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Zhongyu YangKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Jiacheng DongKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Yu ZhangKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China.
Nannan LiuKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China. liunannan@wzu.edu.cn.
Chao DengKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China. dengchao@wzu.edu.cn.
Yajun WangKey Laboratory of Carbon Materials of Zhejiang Province, Key Lab of Biohealth Materials and Chemistry of Wenzhou, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325027, Zhejiang, PR China. yajunwang@wzu.edu.cn.

Funding

the National Natural Science Foundation of China 22175132the Research Project of Wenzhou G2023042the Zhejiang Provincial Natural Science Foundation of China LY24B050003
6 · The paper itself

Abstract

A novel microchannel-based chiral sensor leveraging silica nanowires self-assembled with maltosyl-cyclodextrin (SiNWs/G2-β-CD) on glass microchannel (GMC) is reported. This innovative SiNWs/G2-β-CD/GMC sensor achieves ultrasensitive detection of L-tryptophan over a wide linear range (1-105 aM) with exceptional selectivity, enabling accurate discrimination in mixtures of tryptophan enantiomers. Its application to milk sample analysis demonstrates high recognition performance and practical reliability. The SiNWs/G2-β-CD/GMC sensor offers a rapid, cost-effective, and highly sensitive platform, holding great promise for dietary monitoring and enantiomeric analyses in complex matrices.

Indexed as

Chiral sensorElectrochemical detectionEnantiomer detectionL-TryptophanSiNWs/G2-β-CDVoltammetry

Identifiers

PMID41770375

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.