Evidence map›Paper›PMID 41769997›Full record

ArticleInfection and immunity2026

A Hidden "Promoter":

Jinyuan Zhang, Wenwen Zheng, Yiyan Gong, Xiaofang Jia, Hongli Liu, Fei Guan, Jiahui Lei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinyuan ZhangDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.ORCID 0009-0004-2176-3346
Wenwen ZhengDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.
Yiyan GongDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.
Xiaofang JiaDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.
Hongli LiuCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fei GuanDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-9613-8906
Jiahui LeiDepartment of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-4223-5663

Funding

State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases 2024ZZ10008
6 · The paper itself

Abstract

Schistosomiasis affects approximately 250 million people globally. Eggs deposited in the colon are the main culprits causing pathological damage, with soluble egg antigen (SEA) being the most significant pathogenic factor in schistosomiasis. Colorectal cancer (CRC) is the most common type of gastrointestinal carcinoma. The colorectum is a common organ affected by both CRC and schistosomiasis. Clinical reports have demonstrated a correlation between the onset and poor prognosis of CRC and

Indexed as

Antigens, HelminthAutophagyColorectal NeoplasmsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSchistosoma japonicumSchistosomiasis japonicaAnimalsCell Line, TumorCell ProliferationFemaleHCT116 CellsHumansMiceSignal TransductionAntigens, HelminthPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktautophagycolorectal cancerMAPKPI3K-AKTSchistosoma japonicumsoluble egg antigen

Identifiers

PMID41769997
PMCPMC13081734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.