ReviewFrontiers in nutrition2026
Regulating polysaccharide structure and bioactivity via free radical degradation: a review of mechanisms, effects, and application prospects.
Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Effects of Fermentation and Oxidative Degradation on the Composition, Antioxidant Activity, ACE Inhibitory Activity, and In Vitro Neuroprotective Potential of Soybean-Derived Kefir Polysaccharide-Rich Extracts.Foods (Basel, Switzerland) · 2026Article
- Optimization of Decolorization Process for Crude Polysaccharides fromPlants (Basel, Switzerland) · 2026Article
- Advances in the Preparation, Characterization, and Bioactivity of Oligosaccharides From Traditional Chinese Medicine Polysaccharides: A Comprehensive Review.Chemistry & biodiversity · 2026Review
- Natural polysaccharides as multifunctional anti-cancer agents: structure-activity relationships, mechanisms of action, and therapeutic potential.Frontiers in immunology · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural polysaccharides from food sources (e.g., ginseng, seaweed, apricot, larch) have diverse bioactivities (antioxidant, immunomodulatory, hypoglycemic) that are closely related to human nutritional health, but their structural heterogeneity (e.g., molecular weight, monosaccharide composition) impedes clear structure-activity relationship (SAR) establishment. Free radical degradation, a mild method preserving labile groups (e.g., sulfate esters), is an effective solution. This review summarizes its role in regulating polysaccharide SAR: focusing on hydroxyl radical (⋅OH)-mediated mechanisms (via Fenton-like reactions: processes that generate hydroxyl radicals through the reaction of H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.