Evidence map›Paper›PMID 41769613›Full record

ArticleCureus2026

Primary Vaginal Neuroendocrine Carcinoma: Case Report and Literature Review.

Yanina Nikolaus, Saroj Sigdel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yanina NikolausPathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Saroj SigdelPathology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary small cell carcinoma of the vagina (SmCCV) is exceptionally rare, and its presentation often mimics metastatic disease from more common sites, making diagnosis difficult. In this report, we describe an older woman who came to medical attention with new vaginal bleeding, leading to the discovery of a large vaginal mass. Biopsy findings and whole-body imaging, including positron emission tomography/computed tomography (PET/CT), ultimately supported a primary vaginal origin despite the presence of extensive metastases. Her case illustrates how unusual and clinically challenging this tumor can be, and it emphasizes the need for close collaboration between clinical evaluation, imaging, and pathology to recognize this aggressive malignancy promptly.

Indexed as

atezolizumabcase reportextrapulmonary small cell carcinomahigh-grade neuroendocrine tumorhpv-associated gynecologic malignancyimmunotherapyinsm1 immunohistochemistryplatinum–etoposide chemotherapyprimary small cell carcinoma of the vaginavaginal neuroendocrine carcinoma

Identifiers

PMID41769613
PMCPMC12945341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.