Evidence map›Paper›PMID 41769510›Full record

ReviewCureus2026

Clinical Effectiveness of Barrier Preparations in the Management of Diaper Dermatitis: A Systematic Review and Meta-Analysis.

Zainab Z Alkhamis, Muskaan Bhagchandani, Mumin Idris, Yusuf Bhyat, Sara M Alsani, Arfa I Pasha, Ahmed Hesham Atif Ali, Dhuha Ali Eledresi, Alaa Ahmed Mahdi, Fatimah Ridha Almohamedhusain

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zainab Z AlkhamisPediatrics and Child Health, Gulf Medical University, Ajman, ARE.
Muskaan BhagchandaniInternal Medicine, Thumbay University Hospital, Ajman, ARE.
Mumin IdrisInternal Medicine, Thumbay University Hospital, Ajman, ARE.
Yusuf BhyatGeneral Practice, Gulf Medical University, Ajman, ARE.
Sara M AlsaniFamily Medicine, Dubai Medical College for Girls, Dubai, ARE.
Arfa I PashaSurgery, Sheikh Khalifa Medical City, Abu Dhabi, ARE.
Ahmed Hesham Atif AliInternal Medicine, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, ARE.
Dhuha Ali EledresiGeneral Practice, University of Sharjah, Sharjah, ARE.
Alaa Ahmed MahdiMedicine, Health and Medical Services (HMS) Al Garhoud Private Hospital, Dubai, ARE.
Fatimah Ridha AlmohamedhusainInternal Medicine, Medical University of Warsaw, Warsaw, POL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inflammatory skin condition known as diaper dermatitis (DD) often affects infants and preschoolers. Barrier preparations are commonly used in their management, but their effectiveness remains unclear. This systematic review aimed to evaluate the extent to which barrier preparations reduce DD compared to a placebo or other therapies. To gather relevant information, we conducted electronic searches on databases such as Medical Literature Analysis and Retrieval System Online (MEDLINE) via PubMed, Scopus, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar for data extraction. We included studies based on randomized controlled trials (RCTs), quasi-randomized controlled studies, and cohort studies. The collected data were analyzed using RevMan version 5.3 (The Cochrane Collaboration, London, United Kingdom) for Windows. This study included a total of six studies, comprising four randomized controlled trials and two cohort studies. The analysis focused on the incidence rates of dermatitis among both experimental and placebo groups across approximately four studies. A significant difference in dermatitis prevalence was observed between the intervention and placebo groups (odds ratio {ORs} = 0.77; confidence interval {CI} = 0.37-1.61; p = 0.0002), with notable heterogeneity noted (degrees of freedom {df} = 3; I

Indexed as

barrier creamsbarrier preparationschildrenclinical effectivenessdiaper dermatitisdiaper rashemollientsmeta-analysissystematic reviewtreatment efficacy

Identifiers

PMID41769510
PMCPMC12937271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.