Evidence map›Paper›PMID 41769492›Full record

ArticleCureus2026

A Promise Without Panacea: Psychedelic-Assisted Therapies in Modern Psychiatry.

Mohsin Raza, Jasleen Kaur

Abstract readEditorial
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohsin RazaPsychiatry, Dover Behavioral Health System, Dover, USA.
Jasleen KaurPsychiatry, University of Connecticut Health, Farmington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychedelic-assisted therapies have re-emerged as a subject of increasing scientific and clinical interest in psychiatry, particularly in the context of persistent treatment gaps for conditions such as treatment-resistant depression, post-traumatic stress disorder, and substance use disorders. Compounds, including psilocybin and 3,4-methylenedioxymethamphetamine, are being evaluated in controlled clinical trials and have demonstrated promising therapeutic effects when administered within structured psychotherapeutic frameworks. Emerging neurobiological evidence suggests that these agents may promote neural plasticity and facilitate cognitive and emotional flexibility, potentially enabling durable clinical improvement. Despite these advances, significant challenges remain, including regulatory uncertainty, methodological limitations in existing trials, ethical considerations related to patient vulnerability, and concerns regarding equitable access. This editorial examines the current state of psychedelic-assisted therapies, highlighting both their therapeutic potential and the critical considerations required for their responsible integration into mental health settings.

Indexed as

4-methylenedioxymethamphetamine (mdma)hallucinogenlysergic acid diethylamidemajor depression disorderpost stress traumatic syndromepsilocybinpsychedelic-assisted psychotherapypsychedelics

Identifiers

PMID41769492
PMCPMC12945399

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.