Evidence map›Paper›PMID 41769462›Full record

ArticleCureus2026

The Shape-Shifting Heart: Recurrent Takotsubo Cardiomyopathy Manifesting as Two Variants in One Patient.

Sukhila Reddy, Muhammad Asif, Mounica Vorla, Muhammad Hasib Khalil

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sukhila ReddyCardiology, Carle Foundation Hospital, Urbana, USA.
Muhammad AsifCardiology, Carle Foundation Hospital, Urbana, USA.
Mounica VorlaInternal Medicine, Carle Foundation Hospital, Urbana, USA.
Muhammad Hasib KhalilCardiology, Carle Foundation Hospital, Urbana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo cardiomyopathy (TCM), also known as stress-induced cardiomyopathy, is a transient left ventricular dysfunction that mimics acute coronary syndrome but typically resolves within weeks. Its recurrence is uncommon, and recurrence with distinct morphologic variants is exceedingly rare. We report a 75-year-old female with peripheral arterial disease, paroxysmal atrial fibrillation, sick sinus syndrome status post pacemaker, and prior apical variant TCM in 2022. She underwent a right lower extremity surgery. Two days postoperatively, she developed acute chest pain and troponin elevation. Echocardiography revealed new left ventricular dysfunction with an ejection fraction (EF) of 35-40% and hypokinesis of the anteroseptal and anterior walls. Coronary angiography demonstrated mild nonobstructive coronary artery disease (CAD). Ventriculography confirmed the mid-ventricular variant of TCM. This contrasted with her prior episode in 2022, when she developed apical ballooning variant TCM with an EF of 25-30% during admission for

Indexed as

apical variantmid-ventricular variantstress-induced cardiomyopathytakotsubo cardiomyopathytransient left ventricular dysfunction

Identifiers

PMID41769462
PMCPMC12938004

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.