ArticleResearch and practice in thrombosis and haemostasis2026
Physiologic clot strength by thromboelastography at extremely low and normal platelet counts in thrombocytopenic pregnant patients.
Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Thrombocytopenia in pregnancy poses challenges for neuraxial anesthesia decisions. Guidelines consider platelet counts ≥70×10 Objectives: To evaluate the relationship between thromboelastography (TEG) maximum amplitude (MA) and platelet count in pregnant patients with and without thrombocytopenia, and to determine the ability of MA (across CK, CRT, and CFF assays) to discriminate clinically relevant thrombocytopenia (<70×10⁹/L). Methods: This prospective observational study enrolled pregnant patients with and without thrombocytopenia, defined as platelet count <70×10 Results: Thirty-one patients were enrolled. Log Conclusions: MA strongly correlates with platelet count in thrombocytopenic parturients even at low platelet counts, offering physiologic insight into clot strength and bleeding risk. These findings validate MA as a physiologic correlate of platelet-based clot strength. Thromboelastography may offer complementary physiologic insight into clot strength in parturients with low platelet counts, which can inform-but should not replace-clinical judgment.
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