ArticleArchives of Razi Institute2025
Prevalence of Tuberculosis/COVID 19 Co-Infection among Active Tuberculosis Patients at a Tertiary Care Hospital in Uttarakhand, India.
Article in Archives of Razi Institute, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The Coronavirus disease 2019 (COVID-19) spread all over the world and was accepted as a pandemic by the World Health Organization (WHO) on March 11, 2020. Lungs are predominantly affected by tuberculosis and COVID -19. The objective of the study was to assess the clinical features of COVID-19 in active tuberculosis (pulmonary and extra-pulmonary) and to identify the radiological and laboratory picture of COVID -19 in patients with active tuberculosis. A cross -sectional study was conducted by the Department of Respiratory Medicine, Himalayan Institute of Medical Sciences, among patients of active tuberculosis (pulmonary and extra-pulmonary) who presented to the General Outpatient Department (OPD) of the Respiratory Medicine Department. The questionnaire included questions on socio -demographic profile, clinical features, comorbidities, clinical history, any substance abuse and laboratory investigations. Data was analyzed by SPSS software version 21.0, while Chi-square test was used for categorical data analysis. The mean age of the study participants was 47.5±5.3 years (Range 18-72). Males constituted the larger group (59.38%) as compared to females (40.63%). The prevalence of COVID-19/tuberculosis co-infection in the present study was 21.8%. Positive history of contact, bacterial culture, PCR, and CBNAAT, use of the drug, presence of cavity and pleural effusion on X -Ray, showed all remarkably higher chances (p< 0.05) of developing co-infection. The prevalence of COVID-19/tuberculosis co-infection in the present study was high. Significantly associated factors can help in identifying COVID -19 infection among tuberculosis patients. Therefore, it is recommended that screening for these factors should be done for all tuberculosis patients coming for treatment and Covid 19 vaccination.
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