Bimetallic Au-Ag Nanoclusters as a Photo-Responsive Oxidase-Like Nanozyme for Antioxidant Detection and Intracellular Redox Analysis.

Sanskruti Swain, I-Hsuan Chou, Bikash C Mallick, Shu-Chen Liu, Gin-Shin Chen, Hsing-Ying Lin, Chen-Han Huang

Abstract read

In one paragraph

Article in Small science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Multifunctional Vitamin BAntioxidants (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanskruti SwainDepartment of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan.ORCID https://orcid.org/0009-0002-5403-4129

I-Hsuan ChouDepartment of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan.

Bikash C MallickInstitute of Biomedical Engineering and Nanomedicine National Health Research Institutes Miaoli Taiwan.

Shu-Chen LiuDepartment of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan.

Gin-Shin ChenInstitute of Biomedical Engineering and Nanomedicine National Health Research Institutes Miaoli Taiwan.

Hsing-Ying LinInstitute of Biomedical Engineering National Tsing Hua University Hsinchu Taiwan.ORCID https://orcid.org/0000-0001-9742-3875

Chen-Han HuangDepartment of Biomedical Sciences and Engineering National Central University Taoyuan Taiwan.ORCID https://orcid.org/0000-0002-7021-0797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bimetallic nanoclusters (NCs) hold promise as catalytic materials, yet their potential as enzyme mimics remains largely unexplored. Here, we report the first demonstration that gold-silver nanoclusters (AuAgNCs) function as photo-responsive oxidase-like nanozymes. Under visible-light irradiation, AuAgNCs catalyze thiamine oxidation via a Type I photosensitization pathway, predominantly generating physiologically relevant peroxyl radicals (ROO•). The AuAgNCs outperform monometallic analogs, achieving enhanced catalytic efficiency with lower K

Indexed as

antioxidantgold–silver nanoclustersintracellular redox analysisoxidative stressphoto‐responsive oxidase‐like nanozymereactive oxygen species

Identifiers

PMID41769172

DOI10.1002/smsc.202500560

PMCPMC12948275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.