Evidence map›Paper›PMID 41769149›Full record

ArticleJournal of transplantation2026

Influence of Extended Itraconazole Antifungal Prophylaxis on the Development of Fungal Infections After Lung Transplant.

Sabrina Fischer, Raksha Patel, Mufaddal Mamawala, Susan K Mathai, Katherine Vandervest, Tiana Endicott-Yazdani, Chetan Naik, Todd Grazia, Lisa Fuller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabrina FischerDepartment of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA, mayo.edu.ORCID https://orcid.org/0009-0003-1436-7313
Raksha PatelDepartment of Pharmacy, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0002-4841-0186
Mufaddal MamawalaDepartment of Biostatistics, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0002-5161-3769
Susan K MathaiThe Center for Advanced Lung Disease, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0002-5899-8083
Katherine VandervestThe Center for Advanced Lung Disease, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0003-0234-8302
Tiana Endicott-YazdaniThe Center for Advanced Lung Disease, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0001-7667-1706
Chetan NaikThe Center for Advanced Lung Disease, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0002-5879-9738
Todd GraziaThe Center for Advanced Lung Disease, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0003-2850-9979
Lisa FullerDepartment of Pharmacy, Baylor University Medical Center, Dallas, Texas, USA, baylor.edu.ORCID https://orcid.org/0000-0002-2371-2057

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive fungal infections (IFIs) are associated with a high mortality in lung transplant recipients, with no consensus on optimal antifungal prophylaxis. We aimed to assess the efficacy of long-term itraconazole compared to short-term inhaled amphotericin to prevent IFIs post-transplant. Methods: A retrospective review of adult lung transplant recipients from January 2016 to September 2022 was conducted. The cohort was divided into two groups based on initial mold prophylaxis: long-term itraconazole and short-term inhaled amphotericin. The primary outcome was the incidence of IFIs. The secondary outcomes included the time to IFI, incidence of fungal species found on cultures, and safety/tolerability. Results: A total of 203 patients met the inclusion criteria (amphotericin group Conclusion: In adult lung transplant recipients, long-term prophylaxis with itraconazole was more effective at preventing overall IFIs, positive cultures with

Indexed as

amphotericinantifungal prophylaxisinvasive fungal infectionitraconazolelung transplant

Identifiers

PMID41769149
PMCPMC12938488

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.