ArticleBiomedical optics express2025
Microimager: a flexible thin-film miniaturized endoscope for optical biomedical imaging.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Optical imaging is the gold standard for visualizing the structure and function of biological tissue. Non-invasive imaging methods can only reach a limited depth while providing a high spatial resolution. On the other hand, implantable imagers that can access deep tissue are prohibitively large and invasive. Here, we present the Microimager, a flexible, miniaturized thin-film endoscope (7 × 400 μm) featuring multiple independent channels for high-resolution light delivery and collection from deep tissue. The Microimager consists of an array of parylene photonic waveguides implemented using a scalable microfabrication process. We experimentally demonstrate spatial discrimination and imaging of 30 µm features on a resolution mask, as well as distinct regions in mouse brain tissue. The Microimager is a useful addition to the optical biomedical imaging toolset and can provide access to deep tissue in a minimally invasive way for a wide range of applications.
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