Evidence map›Paper›PMID 41768967›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026

Characterization of Hospitalized Patients With Dengue Fever in Can Tho City: A Cross-Sectional Analysis, 2018-2019.

Thuy Thi Thu Nguyen, Phuong Vu Mai Hoang, Hang Le Khanh Nguyen, Hau Thi Bich Vu, Phuc Van Tran, Truc Minh Huynh, Hung Minh Ha, Thanh Huy Ong, K Morita, F Hasebe and 1 more

Abstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Characterization of Hospitalized Patients With Dengue Fever in Can Tho City: A Cross-Sectional Analysis, 2018-2019.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thuy Thi Thu NguyenVirology Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam, nihe.org.vn.
Phuong Vu Mai HoangVirology Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam, nihe.org.vn.
Hang Le Khanh NguyenVirology Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam, nihe.org.vn.
Hau Thi Bich VuVirology Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam, nihe.org.vn.
Phuc Van TranInfectious Diseases Department, Can Tho City General Hospital, Can Tho City, Vietnam.
Truc Minh HuynhDepartment of Infectious Disease Control and International Health Quarantine, Can Tho Centre for Disease Control and Prevention, Can Tho City, Vietnam.
Hung Minh HaDepartment of Infectious Disease Control and International Health Quarantine, Can Tho Centre for Disease Control and Prevention, Can Tho City, Vietnam.
Thanh Huy OngInfectious Diseases Department, Can Tho Pediatric Hospital, Can Tho City, Vietnam.
K MoritaVirology Department, Institute of Tropical Medicine, Nagasaki University, Nagasaki City, Japan, nagasaki-u.ac.jp.
F HasebeVirology Department, Institute of Tropical Medicine, Nagasaki University, Nagasaki City, Japan, nagasaki-u.ac.jp.
Mai Thi Quynh LeVirology Department, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam, nihe.org.vn.ORCID https://orcid.org/0000-0002-0301-0795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue poses a significant public health issue in tropical and subtropical countries, especially in urban areas. Can Tho, the fourth-largest city in Vietnam's Mekong Delta, is highly vulnerable to climate change. This study characterizes dengue fever (DF) and identifies factors linked to severe disease in hospitalized patients from 2018 to 2019. We analyzed the clinical manifestations of 123 patients, along with blood count tests, RT-PCR, the NS1 antigen rapid test, and ELISA for IgM and IgG antibodies, upon admission. The results revealed that 88.6% of dengue patients were under 15 years, primarily treated at Can Tho Pediatric Hospital, with 66.7% experiencing secondary infections. Warning signs included high fever, rapid pulse, abdominal pain (54.4%), nausea/vomiting (43.2%), and bleeding (5.7%). DEN-1, DEN-2, and DEN-4 circulated during the study, with DEN-1 predominating in 2018 (85.7%) and both DEN-1 and DEN-2 as primary causes in 2019 (52.2% and 39.1%, respectively). The DEN-2 serotype and secondary infections may significantly contribute to severe dengue, and further research on dengue immunity is essential for understanding the effects of dengue vaccination.

Indexed as

dengue fever in Can Tho: warning signshospitalized patientssecondary infections

Identifiers

PMID41768967
PMCPMC12935753

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.