Evidence map›Paper›PMID 41768945›Full record

SynthesisMedecine tropicale et sante internationale2025

[Use of antiparasitic drugs in the prevention of congenital toxoplasmosis: systematic review and meta-analysis].

Richard Amagbégnon, Aretas Babatoundé Nounnagnon Tonouhéwa, Magalie Dambrun, Célia Dechavanne, Aurore Ogouyemi-Hounto, Florence Migot-Nabias, Marie-Laure Dardé, Aurélien Mercier, Dorothée Kindé-Gazard

Abstract readSystematic ReviewMeta-AnalysisEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Medecine tropicale et sante internationale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Richard AmagbégnonCentre hospitalier universitaire de la mère et de lenfant-Lagune (CHU-MEL), 01 BP 107 Cotonou, Bénin.
Aretas Babatoundé Nounnagnon TonouhéwaUnité de recherche sur les maladies transmissibles (URMAT), Université dAbomey-Calavi, 01 BP 2009, Cotonou, Bénin.
Magalie DambrunUniversité Paris Cité, IRD, Inserm, MERIT, 75006 Paris, France.
Célia DechavanneUniversité Paris Cité, IRD, Inserm, MERIT, 75006 Paris, France.
Aurore Ogouyemi-HountoService de microbiologie du Centre national hospitalier universitaire -Hubert Koutoukou MAGA (CNHU-HKM), Université dAbomey-Calavi (UAC), Faculté des sciences de la santé (FSS), Bénin.
Florence Migot-NabiasUniversité Paris Cité, IRD, Inserm, MERIT, 75006 Paris, France.
Marie-Laure DardéInserm U1094, IRD U270, Univ. Limoges, CHU Limoges, EpiMaCT - Épidémiologie des maladies chroniques en zone tropicale, Institut dépidémiologie et de neurologie tropicale, OmegaHealth, CHU de Limoges, 87025 Limoges, France.
Aurélien MercierInserm U1094, IRD U270, Univ. Limoges, CHU Limoges, EpiMaCT - Épidémiologie des maladies chroniques en zone tropicale, Institut dépidémiologie et de neurologie tropicale, OmegaHealth, CHU de Limoges, 87025 Limoges, France.
Dorothée Kindé-GazardService de microbiologie du Centre national hospitalier universitaire -Hubert Koutoukou MAGA (CNHU-HKM), Université dAbomey-Calavi (UAC), Faculté des sciences de la santé (FSS), Bénin.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In the context of preventing congenital Materials and methods: A systematic review of cohort studies published between 2000 and 2023 was conducted to determine the overall risk of mother-to-fetus transmission in pregnant women with primary Results: The average overall risk of maternal-fetal transmission was estimated at 49% (95% CI, 36%-63%) among pregnant women infected during pregnancy who did not receive Conclusion: The failure rate of standard

Indexed as

Antiparasitic AgentsInfectious Disease Transmission, VerticalPregnancy Complications, ParasiticToxoplasmosis, CongenitalFemaleHumansPregnancyPyrimethamineAntiparasitic AgentsPyrimethamineCotrimoxazoleMaternal-fetal transmissionPyrimethamine-sulfadiazinePyrimethamine-sulfadoxineSpiramycinToxoplasma gondiiTreatment failure

Identifiers

PMID41768945
PMCPMC12948362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.