Evidence map›Paper›PMID 41768944›Full record

ArticleMedecine tropicale et sante internationale2025

[Use of genetic material extracted from rapid malaria diagnostic tests using PCR during the Grand Magal of Touba in Senegal].

Coumba Diouf, Ihssane Ouaddane, Georges Diatta, Mamadou Lamine Bara Goumbala, Abdourahmane Sow, Déguène Fam, Mbayang Faye, Philippe Gautret, Cheikh Sokhna

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Medecine tropicale et sante internationale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Coumba DioufAix Marseille Université, Institut de recherche pour le développement (IRD), Assistance publique-Hôpitaux de Marseille (AP-HM), Service de santé des armées (SSA), Maladies infectieuses négligées et émergentes au Sud (MINES), Dakar, Sénégal.
Ihssane OuaddaneAix Marseille Université, IRD, AP-HM, SSA, RITMES, Marseille, France.
Georges DiattaAix Marseille Université, Institut de recherche pour le développement (IRD), Assistance publique-Hôpitaux de Marseille (AP-HM), Service de santé des armées (SSA), Maladies infectieuses négligées et émergentes au Sud (MINES), Dakar, Sénégal.
Mamadou Lamine Bara GoumbalaInstitut hospitalo-universitaire (IHU)-Méditerranée Infection, Marseille, France.
Abdourahmane SowIRD, Université Cheikh Anta Diop (UCAD), MINES, Dakar, Sénégal.
Déguène FamIRD, Université Cheikh Anta Diop (UCAD), MINES, Dakar, Sénégal.
Mbayang FayeIRD, Université Cheikh Anta Diop (UCAD), MINES, Dakar, Sénégal.
Philippe GautretAix Marseille Université, IRD, AP-HM, SSA, RITMES, Marseille, France.
Cheikh SokhnaAix Marseille Université, Institut de recherche pour le développement (IRD), Assistance publique-Hôpitaux de Marseille (AP-HM), Service de santé des armées (SSA), Maladies infectieuses négligées et émergentes au Sud (MINES), Dakar, Sénégal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Grand Magal of Touba (GMT), a religious event, attracts between four and five million pilgrims and poses a significant risk of infectious disease transmission, including malaria. Rapid diagnostic tests (RDTs) are commonly used during the event. This study aimed to validate the use of genetic material extracted from RDTs for retrospective diagnostic testing by PCR. Methods: Two types of RDTs were collected from eight health facilities in the Mbacke department in 2022 and 2023 during the GMT: Bioline™ Malaria Ag P.f/Pan (Abbott, USA) and ParaHIT Results: A total of 2,381 RDTs were collected, 213 of which (8.9%) were positive according to the test readings (135 according to Bioline™ tests, and 78 according to ParaHIT). According to qPCR, 194 samples (8.1%) were positive for Conclusion: Genetic material extracted from RDT cassettes can be used for subsequent PCR diagnosis with increased specificity and sensitivity.

Indexed as

Malaria, FalciparumPlasmodium falciparumHumansPolymerase Chain ReactionRapid Diagnostic TestsReal-Time Polymerase Chain ReactionRetrospective StudiesSenegalSensitivity and SpecificityGrand Magal of ToubaMalariaMbackeRDTSenegalsensitivityspecificitySub-Saharan AfricaTouba

Identifiers

PMID41768944
PMCPMC12948358

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.