Observational studyJNMA; journal of the Nepal Medical Association2025
Normative Data for The Dimensions and Volume of Pituitary Gland in The General Population Undergoing Magnetic Resonance Imaging Under a Tertiary Care Center: An Observational Study.
Observational study in JNMA; journal of the Nepal Medical Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: The pituitary gland is a pivotal neuroendocrine organ responsible for regulating essential physiological functions. Normative data on its dimensions and volume are crucial for identifying pathological changes in clinical settings. However, such reference values are often limited or population-specific. This study aimed to establish normative data for pituitary gland dimensions and volume in the general population undergoing magnetic resonance imaging (MRI) at a tertiary care center. Methods: A total of 870 subjects of all age groups presumed normal pituitary morphology were evaluated using magnetic resonance imaging. Mid sagittal T1 weighted image and coronal T2 weighted images on magnetic resonance imaging were used to measure height, length and width of the pituitary gland. Data was stratified into 10 groups on the basis of age group in each sex to observe the differences. Results: The height and volume of the pituitary gland showed variations with age. Positive correlation was observed between the mean height and volume for the sexes combined which was statistically significant with Pearson correlation coefficient r=0.82 (p<0.001). Conclusions: This study provides normative data for measurements of the pituitary gland and its variations based on age and sex.
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