Evidence map›Paper›PMID 41768799›Full record

ArticleJHLT open2026

Impact of flat chest on waitlist mortality in adult patients with pleuroparenchymal fibroelastosis listed for lung transplantation.

Chihiro Konoeda, Gouji Toyokawa, Miho Yamaguchi, Takafumi Yamaya, Takaki Akamine, Mitsuaki Kawashima, Mototsugu Shimokawa, Masaaki Sato

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Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chihiro KonoedaDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Gouji ToyokawaDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Miho YamaguchiDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Takafumi YamayaDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Takaki AkamineDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Mitsuaki KawashimaDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Mototsugu ShimokawaDepartment of Biostatistics, Graduate School of Medicine, Yamaguchi University, Yamaguchi, Japan.
Masaaki SatoDepartment of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pleuroparenchymal fibroelastosis (PPFE) is a distinct subtype of idiopathic interstitial pneumonia, and progressive cases require lung transplantation (LT). Some patients with PPFE develop chest flattening; however, its impact on waitlist mortality for LT remains unclear. Methods: We retrospectively analyzed adult patients with PPFE listed for LT from donation after brain death (DBD) between January 2014 and July 2024. Chest flatness was quantified as the ratio of the anteroposterior diameter of the thoracic cage to its transverse diameter (APDT/TDT). An APDT/TDT cut-off for waitlist mortality was determined by receiver operating characteristic curve analysis. The primary objective was to investigate the prognostic significance of APDT/TDT on waitlist mortality. Results: Among 36 listed patients, 19 (52.8%) underwent LT, 14 (38.9%) died while awaiting LT, and 3 (8.3%) remained on the waitlist. Patients were classified into high and low APDT/TDT groups: 11 (30.6%) and 25 (69.4%), respectively. The low APDT/TDT group demonstrated shorter 6-minute walk distance (6MWD; Conclusions: The APDT /TDT, an index of a flat chest, may serve as a prognostic factor for waitlist mortality in patients with PPFE awaiting LT.

Indexed as

APDT/TDTFlat chestLung transplantationPleuroparenchymal fibroelastosisWaitlist mortality

Identifiers

PMID41768799
PMCPMC12936945

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