Evidence map›Paper›PMID 41768617›Full record

ArticleACS omega2026

Interactions Involving Neutral Surfactants and Double-Stranded DNA: The Case of Polysorbate 80 (Tween 80).

Arthur G S de Rezende, Márcio S Rocha

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arthur G S de RezendeDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.
Márcio S RochaDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0000-0003-0323-3718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate the interaction of the neutral surfactant polysorbate 80 (Tween 80) with double-stranded DNA under nearly physiological conditions. Single-molecule force spectroscopy assays performed with optical tweezers were used to determine the binding mechanisms below and above the critical micelle concentration (CMC). Below the CMC, individual surfactant molecules bind cooperatively along the double helix, presenting a high equilibrium association constant on the order of 1 × 10

Identifiers

PMID41768617
PMCPMC12946945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.