Evidence map›Paper›PMID 41768535›Full record

ArticleJournal of experimental orthopaedics2026

Palliative high tibial osteotomy achieves comparable outcomes to corrective osteotomy in varus knees with medial compartment osteoarthritis: A long-term clinical and radiological retrospective study.

Alessio Maione, Giuseppe Fedele, Pierrenzo Pozzi, Matteo Davide Parmigiani, Alessandra Menon, Filippo Calanna, Riccardo Compagnoni, Paolo Ferrua, Massimo Berruto, Pietro Simone Randelli

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alessio MaioneU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0002-4464-2254
Giuseppe FedeleU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.
Pierrenzo PozziU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0002-5450-7654
Matteo Davide ParmigianiU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0009-0002-1206-0572
Alessandra MenonU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0003-2786-8099
Filippo CalannaU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0009-0006-4970-3235
Riccardo CompagnoniU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0001-8259-8488
Paolo FerruaU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0002-4408-4248
Massimo BerrutoU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.
Pietro Simone RandelliU.O.C. I Clinica Ortopedica ASST Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0000-0001-9331-820X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The long-term outcomes of palliative high tibial osteotomy (PO) remain insufficiently defined. This study compared the clinical and radiological outcomes of PO with those of corrective osteotomy (CO) in patients with varus knee deformity. Secondary aim was to evaluate arthroplasty-free survival. It was hypothesized that PO and CO would yield comparable results and similar conversion rates to total knee arthroplasty (TKA). Methods: A retrospective cohort study was conducted on patients who underwent lateral closing wedge-high tibial osteotomy (LCW-HTO) between 2001 and 2017. Patients with extra-articular varus deformity (hip-knee-ankle angle [HKA] < 177°, lateral distal femoral angle [LDFA] > 90° or medial proximal tibial angle [MPTA] < 85°) were assigned to the CO group. Those with intra-articular deformity and normal MPTA and LDFA were assigned to the PO group. Radiographic evaluation included HKA, MPTA, LDFA, joint line obliquity (JLO) and joint line convergence angle (JLCA). Clinical outcomes were assessed using the Hospital for Special Surgery (HSS) score, International Knee Documentation Committee (IKDC) subjective score, Numeric Rating Scale (NRS) for pain, Tegner Activity Scale and Crosby-Insall grading. Results: Forty patients were included, 20 in each group. The mean age was 49 ± 11 years, and the mean follow-up was 10.5 ± 2.9 years. Preoperative HKA averaged 174° ± 3.3° and improved to 179° ± 1.5°. Moreover, 25% of PO patients and 10% of CO patients postoperatively exceeded the JLO threshold of ≤4°. Both groups demonstrated significant clinical improvement, with no between-group differences except for higher HSS scores in the PO group. Osteoarthritis (OA) progression was limited, and TKA conversions were infrequent. Conclusion: PO may represent an effective joint-preserving option for intra-articular varus deformity. Despite less optimal correction of JLO and JLCA, PO achieved clinical and radiological outcomes comparable to CO, with similarly low conversion rates to TKA. Level of Evidence: Level IV, retrospective cohort study.

Indexed as

corrective osteotomyhigh tibial osteotomyjoint line obliquitykneelower limb alignmentpalliative osteotomyvarus knee

Identifiers

PMID41768535
PMCPMC12942063

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.