Evidence map›Paper›PMID 41768334›Full record

ArticleJournal of surgical case reports2026

Multifactorial etiology of oral pyogenic granuloma: case reports with distinct triggers.

Francisco Javier Alcaraz-Baturoni, Jessica Paola Ibarra-González, Mario Alberto Alarcón-Sánchez, Giselle Berenice Vela-Sancho, Javier Flores-Fraile, Artak Heboyan, Rocio Del Carmen Anaya-Macías, Sarah Monserrat Lomelí-Martínez

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In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francisco Javier Alcaraz-BaturoniDepartment of Integral Dental Clinics, University Center of Health Sciences, University of Guadalajara (CUCS-UdeG), Sierra Mojada 950, Colonia Independencia Oriente, Guadalajara 44340, Jalisco, Mexico.ORCID https://orcid.org/0009-0008-5595-2881
Jessica Paola Ibarra-GonzálezDepartment of Integral Dental Clinics, University Center of Health Sciences, University of Guadalajara (CUCS-UdeG), Sierra Mojada 950, Colonia Independencia Oriente, Guadalajara 44340, Jalisco, Mexico.ORCID https://orcid.org/0009-0007-7967-1411
Mario Alberto Alarcón-SánchezMolecular Biology and Medicine Program, Molecular Biology Department, University Center of Health Sciences, University of Guadalajara (CUCS-UdeG, Sierra Mojada 950, Colonia Independencia Oriente, Guadalajara 44340, Jalisco, Mexico.ORCID https://orcid.org/0000-0001-6727-7969
Giselle Berenice Vela-SanchoLaboratory of Molecular Neuroimmunobiology, Institute of Translational Neurosciences, Department of Molecular Biology and Genomics, University Center for Health Sciences, University of Guadalajara (CUCS-UdeG), Sierra Mojada 950, Colonia Independencia Oriente, Guadalajara 44340, Jalisco,  Mexico.ORCID https://orcid.org/0000-0003-2322-3111
Javier Flores-FraileDepartment of Surgery, Faculty of Medicine, University of Salamanca, Campus Miguel de Unamuno, 37008 Salamanca, Spain.
Artak HeboyanDepartment of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600 077, India.ORCID https://orcid.org/0000-0001-8329-3205
Rocio Del Carmen Anaya-MacíasDepartment of Medical and Life Sciences, La Ciénega University Center, University of Guadalajara (CUCIENEGA-UdeG), Avenida Universidad 115, Colonia LindaVista, Ocotlán 47810, Jalisco, Mexico.ORCID https://orcid.org/0009-0007-8947-2109
Sarah Monserrat Lomelí-MartínezDepartment of Medical and Life Sciences, La Ciénega University Center, University of Guadalajara (CUCIENEGA-UdeG), Avenida Universidad 115, Colonia LindaVista, Ocotlán 47810, Jalisco, Mexico.ORCID https://orcid.org/0000-0002-0569-1387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyogenic granuloma (PG) is a common reactive vascular hyperplasia of the oral cavity with multifactorial origin. Although benign, it shows clinical variability and may recur if predisposing factors persist. This report describes two oral PG cases with different etiologies. A 68-year-old man presented with a mucogingival lesion associated with dental calculus, while a 29-year-old woman developed a lesion during pregnancy that continued after delivery. Both were treated with complete surgical excision and elimination of local irritants. Histopathology confirmed PG, characterized by granulation tissue rich in vascular spaces, inflammatory infiltrate, and areas of epithelial ulceration. Follow-up visits showed good healing and no recurrence. These cases emphasize the interaction of local agents like calculus and biofilm with systemic factors such as gestational hormonal changes. PG management requires identifying contributing factors and performing thorough surgical removal, though alternative methods-cryosurgery, electrosurgery, or laser-may be useful in selected scenarios.

Indexed as

capillary hemangiomahyperplastic lesionlobulated vascular lesionoral surgerypyogenic granuloma

Identifiers

PMID41768334
PMCPMC12941191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.