Evidence map›Paper›PMID 41768260›Full record

ReviewFrontiers in oncology2026

PICU associated social-emotional adversity in early childhood cancer patients: consequences in neurodevelopment and mental health.

Maria Kroupina, Quannah Parker-McGowan, Madeline Kotz, Arif Somani

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria KroupinaDepartment of Pediatrics, Division of Clinical Behavioral Neuroscience, University of Minnesota, Minneapolis, MN, United States.
Quannah Parker-McGowanDepartment of Pediatrics, Division of Clinical Behavioral Neuroscience, University of Minnesota, Minneapolis, MN, United States.
Madeline KotzDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, University of Minnesota, Minneapolis, MN, United States.
Arif SomaniDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, University of Minnesota, Minneapolis, MN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we propose that PICU hospitalization accentuates extreme early social-emotional adversity and compounds hospital-associated trauma that may result in neurodevelopmental and mental health challenges for pediatric cancer survivors. We focus specifically on the first three years of life, when the incidence of childhood cancer is the highest and the brain is in its most vulnerable period of development. A comprehensive understanding of risks associated with PICU hospitalization is necessary for informing improvements to the inpatient environment and proposing new models for administering mental health care, evidence-based intervention, and long-term follow-up.

Indexed as

early childhood cancermental healthneurodevelopmentPICU hospitalizationsocial-emotional adversity

Identifiers

PMID41768260
PMCPMC12945750

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.