ArticleFrontiers in oncology2026
The value of T1 mapping and intravoxel incoherent motion parameters in predicting PD-L1 expression and dynamically monitoring immunotherapy in advanced lung cancer.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the value of T1 mapping and intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) quantitative parameters in predicting PD-L1 expression and dynamically monitoring immunotherapy efficacy in advanced lung cancer. Materials and methods: 23 patients pathologically diagnosed with advanced lung cancer were collected. Patients underwent T1 mapping and IVIM examinations pre- and post-immunotherapy. The relationship between PD-L1 expression levels and quantitative parameters was analyzed. The changes of quantitative parameters during treatment were compared between the effective and ineffective groups. The predictive value of quantitative parameters for immunotherapy efficacy was analyzed using area under the curve (AUC). Results: In terms of predicting PD-L1 expression, there were no significant differences in the T1, apparent diffusion coefficient (ADC), perfusion fraction (f), true diffusion coefficient (D), and pseudo-diffusion coefficient (D*) values between the positive and negative groups (all Conclusion: T1 mapping and IVIM quantitative parameters may reflect potential trends in predicting PD-L1 expression, have certain value in monitoring the dynamic changes during immunotherapy in advanced lung cancer, and are expected to provide meaningful imaging biomarkers for individualized immunotherapy decision-making.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.