Evidence map›Paper›PMID 41767942›Full record

ArticleBiomedical optics express2025

Snapshot hyperspectral imaging microscope enabled by cladded waveguide array fabricated with 2-photon additive manufacturing.

Haimu Cao, Roger McNichols, Clayton B Walker, Brian Applegate, Tomasz S Tkaczyk

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haimu CaoDepartment of Electrical and Computer Engineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.ORCID https://orcid.org/0009-0001-9448-029X
Roger McNicholsDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, Texas 77005, USA.
Clayton B WalkerDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, Texas 77005, USA.
Brian ApplegateCaruso Department of Otolaryngology-Head & Neck Surgery, University of Southern California, 1450 San Pablo Street, Los Angeles, California 90033, USA.ORCID https://orcid.org/0000-0003-2795-5678
Tomasz S TkaczykDepartment of Electrical and Computer Engineering, Rice University, 6100 Main Street, Houston, Texas 77005, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snapshot spectrometers capture spatial and spectral data in real-time, offering transformative potential in biomedical imaging and environmental monitoring. However, conventional designs struggle to reconcile high spatial-spectral sampling density with device miniaturization. To address this, we present a compact snapshot imaging spectrometer leveraging a densely packed 3D waveguide array fabricated via two-photon polymerization (2PP), an additive manufacturing technique that achieves submicron precision in complex geometries. The design features 26,000 straight waveguides in an angled end-face configuration, with a 4 µm pitch and 2.5 µm core size. By introducing a vertical layer height increment of 32 µm, the array facilitates spectral data distribution across 40 pixels. The compact structure, measuring 852 µm x 552 µm x 4093 µm, offers new opportunities for integrating snapshot spectroscopy into portable devices. The system's performance is evaluated through measurements of spectral resolution, crosstalk, and throughput. Validation using USAF resolution target imaging and the biological microscopic samples demonstrates its potential to deliver accurate and high-efficiency spectral data.

Identifiers

PMID41767942
PMCPMC12945494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.