ArticleBiomedical optics express2025
Ultrafast line-field holographic elastography with single excitation for corneal biomechanical characterization.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elastography has become an essential tool for assessing tissue biomechanics, in particular for the diagnosis and treatment of keratoconus. For in vivo measurements, high-speed imaging and reduced stimulation are crucial. In this study, we introduce a line-field holographic elastography (LF-HE), which employs line-focus illumination and parallel acquisition to achieve ultra-fast measurement in 14 ms with single excitation. A novel data processing method combining the short time Fourier transform, the phase-resolved color Doppler and full width at half maximum algorithms is proposed to extract the local biomechanical property. Agar phantoms with various concentrations were measured to valid the LF-HE system. The changes of stiffness of in situ porcine corneas treated by riboflavin/UV-A collagen cross-linking (UV-CXL) were also detected in a lateral range of 4.4 mm by modifying the light path of sample arm. This research demonstrated the significant potential of LF-HE for application in ophthalmology clinics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.