Evidence map›Paper›PMID 41767924›Full record

ArticleBiomedical optics express2025

Quantitative fs-laser crystalline lens softening surgery towards presbyopia treatment based on optical coherence elastography.

Zhuoyu Zhang, Haijun Lv, Hao Zhang, Ying Zhang, Bingxi Wang, Yinan Liao, Zimeng Zhou, Jun Deng, Ruonan Bian, Shangbin Chen and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zhuoyu ZhangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.ORCID https://orcid.org/0000-0001-6298-2589
Haijun LvBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Hao ZhangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Ying ZhangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Bingxi WangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Yinan LiaoBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Zimeng ZhouBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Jun DengBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Ruonan BianBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Shangbin ChenBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Tingwei QuanBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Xiuli LiuBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Honghao WangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.ORCID https://orcid.org/0000-0002-1622-0417
Jing WangBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.ORCID https://orcid.org/0000-0001-7234-4388
Peng LiState Key Lab of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0000-0002-9652-2369
Xiaohua LvBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Shaoqun ZengBritton Chance Center for Biomedical Photonics, MOE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presbyopia, a prevalent age-related vision disorder, is primarily characterized by the progressive loss of accommodative ability due to crystalline lens hardening, as described by the Helmholtz theory of accommodation. Among emerging presbyopia correction techniques, femtosecond laser lentotomy (fs-lento) has gained attention for its potential to restore accommodative function through the creation of intracapsular gliding planes via laser-induced optical breakdown (LIOB). This approach offers distinct advantages, including potential accommodative recovery, a non-invasive nature, minimal tissue disruption, and negligible bleeding risk. However, despite two decades of technical development, the clinical translation of fs-lento remains hindered by challenges in quality control and outcome heterogeneity, primarily due to the absence of precise quantitative methods for assessing the surgical effects on tissue mechanical properties. To address these limitations, we developed a femtosecond laser ocular research apparatus (FLORA) system for surgical investigations. Furthermore, we implemented a novel PZT-contact optical coherence elastography (OCE) system, modified from SD-OCT and validated through phantom experiments, for quantitative tissue mechanical characterization. Our experimental results using

Identifiers

PMID41767924
PMCPMC12945495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.