Evidence map›Paper›PMID 41767916›Full record

ArticleBiomedical optics express2025

Ultrafast laser bone ablation towards high surgical speeds and clinically relevant operation times for spine surgeries.

Biswajit Mishra, Liam Andrus, Aditya Roy, Berk Camli, Fetah Benabid, Adela Ben-Yakar

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Biswajit MishraDepartment of Mechanical Engineering, The University of Texas at Austin Austin, TX, USA.
Liam AndrusDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA.
Aditya RoyDepartment of Mechanical Engineering, The University of Texas at Austin Austin, TX, USA.
Berk CamliDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA.
Fetah BenabidGPPMM Group, XLIM Institute, UMR CNRS 7252, University of Limoges, Limoges 87060, France.ORCID https://orcid.org/0000-0001-9705-4846
Adela Ben-YakarDepartment of Mechanical Engineering, The University of Texas at Austin Austin, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in ultrafast laser ablation technology redefine surgical precision while minimizing thermal damage, offering a promising alternative to traditional methods. However, the slow material removal rates (MRRs) have hindered clinical adoption. Addressing this challenge, we present a compact fiber-based laser delivery system, exhibiting an 82-fold increase in MRR compared to previous femtosecond laser probes. The system leverages a hollow-core Kagome fiber to deliver 10 ps laser pulses with high transmission efficiency and minimal nonlinear effects, even at high peak powers. The system distributes ultrashort pulses utilizing a piezo-scanned Lissajous-based beam steering mechanism onto the target surface over a larger field-of-view (FOV), enabling the scope for easy scalability of the system to a miniaturized probe. Drawing insights from our prior work, the focusing optics were carefully selected to deliver fluence three times the ablation threshold. An optimal combination of FOV size, translation speed, and repetition rate was identified, enabling clean ablations (devoid of carbonization) even at maximum laser power. We achieved a maximum MRR of 10.7 mm

Identifiers

PMID41767916
PMCPMC12945503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.