Evidence map›Paper›PMID 41767743›Full record

ArticleInternational journal of cardiology. Cardiovascular risk and prevention2026

Early cardiac rehabilitation supported by levosimendan infusion and mitral valve repair in acute myocardial infarction complicated by cardiogenic shock.

Alessandro Villaschi, Silvia Di Lauro, Fabrizio Calloni, Anastasia Toccafondi, Jacopo Oreglia, Alice Sacco, Nuccia Morici

Abstract readCase Reports
In one paragraph

Article in International journal of cardiology. Cardiovascular risk and prevention, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Alessandro VillaschiCardiac Rehabilitation, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Silvia Di LauroCardiac Rehabilitation, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Fabrizio CalloniCardiac Rehabilitation, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Anastasia ToccafondiCardiac Rehabilitation, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Jacopo OregliaDe Gasperis Cardio Center, Niguarda Hospital, Milan, Italy.
Alice SaccoDe Gasperis Cardio Center, Niguarda Hospital, Milan, Italy.
Nuccia MoriciCardiac Rehabilitation, IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with acute ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock and severely reduced left ventricular ejection fraction (LVEF) face extremely poor prognosis, particularly elderly patients. Early initiation of cardiac rehabilitation is often limited by haemodynamic instability. Case summary: A 75-year-old man with anterior STEMI treated with primary percutaneous coronary revascularization experienced multiple complications including cardiogenic shock, multiorgan dysfunction, persistent ventricular arrhythmias and severe mitral regurgitation (MR). Via a strong collaboration between a tertiary cardiac centre and rehabilitation facility, recurrent decompensation was treated with early administration of ino-dilators, mitral transcatheter edge-to-edge repair (M-TEER) and a tailored cardiac rehabilitation programme, providing net improvement in clinical stability, functional capacity and subsequent clinical outcomes. Conclusion: This case highlights the potential role of early haemodynamic stabilization with levosimendan, M-TEER and multidisciplinary rehabilitation in improving functional outcomes, even in high-risk elderly patients with STEMI complicated by cardiogenic shock and severely reduced LVEF.

Indexed as

Acute myocardial infarctionCardiac rehabilitationLevosimendan

Identifiers

PMID41767743
PMCPMC12936560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.