Evidence map›Paper›PMID 41767609›Full record

ArticleCase reports in ophthalmological medicine2026

Bilateral Simultaneous Acute Angle-Closure Glaucoma Following Over-the-Counter Cold Medication.

Chiara Vivarelli, Marco Pellegrini, Francesco Parmeggiani, Ginevra Giovanna Adamo, Carla Enrica Gallenga, Paola Ferri, Marco Mura

Abstract read
In one paragraph

Article in Case reports in ophthalmological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chiara VivarelliOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.ORCID https://orcid.org/0009-0004-5139-254X
Marco PellegriniOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.
Francesco ParmeggianiOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.
Ginevra Giovanna AdamoOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.
Carla Enrica GallengaOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.
Paola FerriDepartment of Biomedical Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy, unimore.it.
Marco MuraOphthalmology Clinic Operating Unit, Head and Neck Department, Arcispedale Sant'Anna University Hospital, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We report a case of bilateral acute angle-closure glaucoma occurring concurrently after the intake of dextromethorphan, a commonly used over-the-counter medication for flu symptom relief. Case Presentation: A 65-year-old woman presented with bilateral acute angle-closure glaucoma following 5 days of treatment with an OTC medication. Her intraocular pressures (IOPs) were 57 mmHg in the right eye and 50 mmHg in the left. Slit lamp biomicroscopy revealed shallow anterior chambers bilaterally, and gonioscopy confirmed angle closure. Management involved immediate discontinuation of the offending medication, initiation of antiglaucoma treatment, and bilateral Nd: YAG laser iridotomy, which successfully normalized IOP and resolved the angle-closure attack. Conclusion: This case highlights that commonly used OTC cold and flu remedies can trigger acute angle-closure glaucoma, particularly in predisposed individuals. Early diagnosis and prompt intervention are crucial to prevent vision loss.

Indexed as

bilateral acute angle-closure glaucomacase reportdrug-induced acute angle-closure glaucomamydriasisover-the-counter flu medication

Identifiers

PMID41767609
PMCPMC12947831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.