ArticleFrontiers in microbiology2026
The gp38 protein inhibits host adsorption of phage vB_EcoM_SD286.
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Bacteriophages (phages), which are viruses that infect bacteria, primarily use surface receptor-binding proteins (RBPs) to recognize and infect their hosts. Elucidating the function of specific RBPs is crucial for understanding phage-host interactions and developing phage-based antimicrobials. Methods: This study characterized the Results: Phage vB_EcoM_SD286 exhibited an icosahedral head and a helical tail, classifying it within the Conclusion: Collectively, our findings provide preliminary evidence that gp38 is involved in the phage-host interaction of vB_EcoM_SD286, likely functioning as a receptor-binding protein. This study offers a theoretical basis for elucidating the precise bacterial receptor recognition mechanism and lays the groundwork for future development of phage-based antimicrobial agents.
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