Evidence map›Paper›PMID 41767554›Full record

ArticleJournal of diabetes research2026

Identifying Provider Prescribing Practices for GLP-1RAs and SGLT-2is in Patients With Type 2 Diabetes to Address Pharmacoinequity.

Parnnate Wongsirisakul, Vincent L Chen, Ponni V Perumalswami

Abstract read
In one paragraph

Article in Journal of diabetes research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Parnnate WongsirisakulDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA, umich.edu.ORCID https://orcid.org/0009-0009-6711-1761
Vincent L ChenDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA, umich.edu.ORCID https://orcid.org/0000-0002-0157-6066
Ponni V PerumalswamiDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA, umich.edu.ORCID https://orcid.org/0000-0003-3070-3906

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

Background and Aims: Evidence-based treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with Type 2 diabetes (T2DM) focuses on glycemic control and lifestyle modification to achieve weight loss, which slows the progression of liver disease and reduces the risk of liver-related complications. We aimed to qualitatively explore provider-level determinants in glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium/glucose cotransporter 2 inhibitors (SGLT-2is) prescription. Methods: We identified a cohort of 189 outpatient adult primary care providers who cared for at least 50 annual T2DM patients in a tertiary academic health system in the United States in 2021. GLP-1RA and SGLT-2i prescribing rates were calculated with a median rate of 0.494 (IQR 0.393-0.594). Guided by the Consolidate Framework for Implementation Research, we conducted 1:1 interviews with high-prescribing and low-prescribing providers. All providers interviewed were either MDs or DOs. Results: Nine providers from the high-prescribing quartile (prescribing rate 59.5%-78.6%) and eight from the low-prescribing quartile (prescribing rate 4.8%-39.3%) were interviewed. High-prescribing providers reported more patient-facing hours and exposure to GLP-1RAs and SGLT-2is in residency. All providers cited task-sharing, patient-provider relationship longevity, and medication effectiveness as facilitators of GLP-1RA and SGLT-2i prescription. Barriers to prescribing included medication costs, prior authorization processes, and prescription inertia. Using the Expert Recommendations for Implementing Change, we mapped barriers and facilitators to implementation strategies. Conclusions: This interview series identified key barriers and facilitators of GLP-1RA and SGTL-2i prescription. Implementation strategies may help improve prescribing highly effective, newer treatments in patients with T2DM, including those with metabolic comorbidities.

Indexed as

Diabetes Mellitus, Type 2Glucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsPractice Patterns, Physicians'Sodium-Glucose Transporter 2 InhibitorsFemaleHumansMaleMiddle AgedUnited StatesGlucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsSodium-Glucose Transporter 2 InhibitorsGLP-1RAliver diseasepharmacoequityprovider interviewSGLT-2iType 2 diabetes

Identifiers

PMID41767554
PMCPMC12943470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.