Evidence map›Paper›PMID 41767348›Full record

ArticleHealth science reports2026

Knowledge of Local Anesthetic Toxicity Among Healthcare Workers in Surgical Departments: A Hospital-Based, Cross-Sectional Study in Vietnam.

Vu Tri Thanh, Le Ngo Khai Vy, Giap Thi Mai Linh, Tran Hoai Huy, Le Diep Bao Liem, Nguyen Huu Khanh Linh, Vo Y Lan, Nguyen Kim Anh, Ho Tat Bang

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Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Vu Tri ThanhThu Duc General Hospital Ho Chi Minh City Vietnam.
Le Ngo Khai VyPreventive Medicine Class of 2021, Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.
Giap Thi Mai LinhPreventive Medicine Class of 2021, Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.ORCID https://orcid.org/0009-0007-6783-6936
Tran Hoai HuyPreventive Medicine Class of 2021, Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.
Le Diep Bao LiemPreventive Medicine Class of 2021, Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.
Nguyen Huu Khanh LinhPreventive Medicine Class of 2021, Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.
Vo Y LanKanagawa University of Human Services Yokosuka Japan.ORCID https://orcid.org/0000-0001-5962-2822
Nguyen Kim AnhThu Duc General Hospital Ho Chi Minh City Vietnam.
Ho Tat BangUniversity Medical Center Ho Chi Minh City, University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.ORCID https://orcid.org/0000-0002-6786-1644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Local anesthetic systemic toxicity (LAST) is a rare but potentially life-threatening complication associated with the use of local anesthetics. Prompt recognition and effective management are critical to preventing severe outcomes. However, studies have shown that healthcare workers' knowledge regarding LAST remains limited, especially in surgical settings where local anesthetics are frequently used. This study is to assess the current state and associated factors of knowledge regarding LAST among healthcare workers in the surgical departments of a hospital under the Ho Chi Minh City Department of Health. Methods: A cross-sectional study was conducted from April 2024 to May 2025, involving 260 healthcare workers across 11 clinical departments. Data were collected using a structured, self-administered questionnaire developed based on national guidelines for LAST diagnosis and management. Results: Nearly half of the participants (48.8%, 127/260) reported having prescribed or administered local anesthetics. Among those with direct experience using local anesthetics, lidocaine was the most commonly used agent (88.2%, 112/127). The majority of participants (81.9%, 213/260) correctly recognized that local anesthetic systemic toxicity (LAST) may occur even when local anesthetics are administered within recommended dosage ranges. However, only 22.3% (58/260) perceived themselves as knowledgeable about LAST. Regarding lipid emulsion therapy, 33.8% (88/260) reported having heard of 20% lipid emulsion therapy, whereas 43.9% (114/260) had never heard of this intervention. The most frequently identified early signs of LAST were tachycardia (64.6%, 168/260) and hypertension (34.2%, 89/260). Conclusion: Healthcare workers in surgical departments demonstrated insufficient knowledge regarding local anesthetic toxicity, particularly in recognizing early symptoms and understanding the use of lipid emulsion therapy as a treatment strategy. Targeted training programs are warranted to enhance competency in LAST management and improve patient safety.

Indexed as

Healthcare knowledgeLipid emulsion therapyLocal anesthetic toxicity

Identifiers

PMID41767348
PMCPMC12946651

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